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10.1007/s00059-012-3656-3

http://scihub22266oqcxt.onion/10.1007/s00059-012-3656-3
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22872003!ä!22872003

suck abstract from ncbi


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pmid22872003      Herz 2012 ; 37 (6): 637-43
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  • miRNA as activity markers in Parvo B19 associated heart disease #MMPMID22872003
  • Kuhl U; Rohde M; Lassner D; Gross UM; Escher F; Schultheiss HP
  • Herz 2012[Sep]; 37 (6): 637-43 PMID22872003show ga
  • Parvovirus B19 is a frequent virus detected in endomyocardial biopsies of patients with clinically suspected myocarditis or dilated cardiomyopathy (DCM). Viruses often cause a more symptomatic disease with increased tissue injury if they become reactivated. A disease-specific differential expression of microRNAs (miRNAs) has been described in the regulation of replicating viruses. Analyzing patients with latent and reactivated B19V infection, we found 29 differentially regulated miRNAs and, in order to test whether predicted genes are differentially expressed, selected mRNAs were tested by TaqMan-QPCR.
  • |Cardiomyopathies/diagnosis/*genetics/*virology[MESH]
  • |Female[MESH]
  • |Genetic Markers/*genetics[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |MicroRNAs/*genetics[MESH]
  • |Middle Aged[MESH]
  • |Parvoviridae Infections/diagnosis/*genetics/*virology[MESH]


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