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10.1002/ppul.22621

http://scihub22266oqcxt.onion/10.1002/ppul.22621
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22833544!7167945!22833544
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suck abstract from ncbi


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pmid22833544      Pediatr+Pulmonol 2013 ; 48 (5): 481-9
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  • Vitamin A deficiency alters airway resistance in children with acute upper respiratory infection #MMPMID22833544
  • Amaral CT; Pontes NN; Maciel BL; Bezerra HS; Triesta AN; Jeronimo SM; McGowan SE; Dantas VM
  • Pediatr Pulmonol 2013[May]; 48 (5): 481-9 PMID22833544show ga
  • OBJECTIVE: To assess whether vitamin A deficiency alters the recovery of total respiratory resistance (TRR) following acute upper respiratory tract infection (URI). METHODS: This is a case control study of children, age 4-6 years and grouped as: URI, (n = 74), URI and wheezing, (URI-wheezing, n = 52), and healthy controls (n = 51). Vitamin A and total respiratory resistance (TRR) were assessed using the modified relative dose response (MRDR) and forced oscillometry, respectively. RESULTS: Children with URI and URI-wheezing had lower retinol, 32.4 +/- 13.12 and 18.3 +/- 6.83 microg/dl respectively, compared to controls, 56.9 +/- 29.82 microg/dl (ANOVA, P < 0.001). The MRDR was elevated in children in the URI or URI-wheezing groups 0.066 +/- 0.045 and 0.021 +/- 0.021, respectively, compared to controls 0.007 +/- 0.006 (ANOVA, P < 0.0001). The TRR in the URI and URI-wheezing groups differed from controls. During convalescence, the TRR failed to decline in the URI-group only when the MRDR was >0.06. In the URI-wheezing group, TRR declined independently of retinol and MRDR. CONCLUSION: Vitamin A contributes to preservation of airway function during and in recovery after upper respiratory infection in children.
  • |*Airway Resistance[MESH]
  • |C-Reactive Protein/analysis[MESH]
  • |Case-Control Studies[MESH]
  • |Child[MESH]
  • |Child, Preschool[MESH]
  • |Comorbidity[MESH]
  • |Cross-Sectional Studies[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Respiratory Sounds/physiopathology[MESH]
  • |Respiratory Tract Infections/*epidemiology/*physiopathology[MESH]
  • |Vitamin A Deficiency/*epidemiology/*physiopathology[MESH]


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