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10.1002/ppul.22608

http://scihub22266oqcxt.onion/10.1002/ppul.22608
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22778084!7168025!22778084
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suck abstract from ncbi


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pmid22778084      Pediatr+Pulmonol 2013 ; 48 (4): 390-7
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  • A 4 year prospective study to determine risk factors for severe community acquired pneumonia in children in southern China #MMPMID22778084
  • Zhang Q; Guo Z; Bai Z; MacDonald NE
  • Pediatr Pulmonol 2013[Apr]; 48 (4): 390-7 PMID22778084show ga
  • BACKGROUND: Pneumonia is the major cause of death under 5 years. With high CAP numbers in China and growing access to PICUs, factors associated with severe CAP need to be determined to optimize care. OBJECTIVE: To prospectively determine PICU CAP admission features and outcomes. METHODS: A 4 year prospective study of CAP aged 1 month to <14 years admitted to PICU, Children's Hospital Affiliated to Soochow University, China. All were managed in a standard manner. Clinical, laboratory, and imaging findings were collected systematically. All received antibiotics. RESULTS: Eight hundred ten (7%) of 10,836 CAP hospital admissions needed PICU. Seven hundred seven (87%) were enrolled. PICU CAP children were young (76% 70/min, grunting/groaning, head nodding, cyanosis, and anemia were associated with respiratory failure and with fatality. On multivariate analysis only presence of congenital heart disease, Trisomy 21 and immunodeficiency correlated with fatality; not microbe nor PICU findings. CONCLUSIONS: Young age and underlying congenital heart disease were associated factors for PICU support in CAP in China. Early referral if altered sensorium, high respiratory rate, head nodding, grunting and anemia, and universal access to conjugated vaccines may decrease morbidity and mortality.
  • |*Critical Care/methods/statistics & numerical data[MESH]
  • |*Severity of Illness Index[MESH]
  • |Adolescent[MESH]
  • |Child[MESH]
  • |Child, Preschool[MESH]
  • |China/epidemiology[MESH]
  • |Community-Acquired Infections/etiology/mortality/therapy[MESH]
  • |Female[MESH]
  • |Hospitalization/statistics & numerical data[MESH]
  • |Hospitals, Pediatric/statistics & numerical data[MESH]
  • |Humans[MESH]
  • |Infant[MESH]
  • |Intensive Care Units, Pediatric/statistics & numerical data[MESH]
  • |Logistic Models[MESH]
  • |Male[MESH]
  • |Pneumonia/*etiology/mortality/therapy[MESH]
  • |Prospective Studies[MESH]
  • |Risk Factors[MESH]


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