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http://scihub22266oqcxt.onion/ 2277603!ä!2277603 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Miner+Electrolyte+Metab 1990 ; 16 (4): 197-201 Nephropedia Template TP {{tp|p=2277603|t=1990. Intracellular alkalosis induced by increasing extracellular potassium Ionic dependence and effects of amiloride and DIDS |pdf=|usr=}}{{2277603}} gab.com Text Intracellular alkalosis induced by increasing extracellular potassium Ionic dependence and effects of amiloride and DIDS JO: Miner Electrolyte Metab http://www.kidney.de/pget.php?&tw=1&pmid=2277603 #FOAvip The intracellular alkalinization produced when extracellular potassium concentration is increased above its normal levels was studied in the rat diaphragm muscle by determination of the steady-state distribution of [14C]-5,5-dimethyl-2,4-oxazolidinedione (DMO). Replacement of external Na+ with sucrose and Mg2+ or N-methyl-D-glucamine prevented the rise in intracellular pH. Amiloride (1 mM) also abolished the elevation of intracellular pH, while the removal of external Cl- (replaced by gluconate) or addition of 0.1 mM 4-acetamido-4'-diisothyocyanostilbene-2,2-disulfonic acid (DIDS) did not prevent intracellular alkalinization from taking place. These results suggest that in the rat diaphragm muscle a Na(+)-dependent, amiloride-sensitive transport mechanism, perhaps Na+/H+ exchange, plays a major role in the K(+)-induced intracellular alkalinization. This mechanism might account for the metabolic acidosis produced by hyperkalemia. Twit Text FOAVip Intracellular alkalosis induced by increasing extracellular potassium Ionic dependence and effects of amiloride and DIDS ????Miner Electrolyte Metab http://www.kidney.de/pget.php?&tw=1&pmid=2277603 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=2277603 #FOAvip English Wikipedia <ref>{{Cite pmid|2277603}}</ref> Intracellular alkalosis induced by increasing extracellular potassium Ionic dependence and effects of amiloride and DIDS #MMPMID2277603 Altenberg GA Miner Electrolyte Metab 1990[]; 16 (4): 197-201 PMID2277603show ga The intracellular alkalinization produced when extracellular potassium concentration is increased above its normal levels was studied in the rat diaphragm muscle by determination of the steady-state distribution of [14C]-5,5-dimethyl-2,4-oxazolidinedione (DMO). Replacement of external Na+ with sucrose and Mg2+ or N-methyl-D-glucamine prevented the rise in intracellular pH. Amiloride (1 mM) also abolished the elevation of intracellular pH, while the removal of external Cl- (replaced by gluconate) or addition of 0.1 mM 4-acetamido-4'-diisothyocyanostilbene-2,2-disulfonic acid (DIDS) did not prevent intracellular alkalinization from taking place. These results suggest that in the rat diaphragm muscle a Na(+)-dependent, amiloride-sensitive transport mechanism, perhaps Na+/H+ exchange, plays a major role in the K(+)-induced intracellular alkalinization. This mechanism might account for the metabolic acidosis produced by hyperkalemia. |4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid[MESH] |4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid/*analogs & derivatives/pharmacology[MESH] |Alkalosis/*chemically induced[MESH] |Amiloride/*pharmacology[MESH] |Animals[MESH] |Cell Membrane/drug effects/metabolism[MESH] |Chlorides/metabolism[MESH] |Diaphragm/*drug effects/metabolism[MESH] |Hydrogen-Ion Concentration[MESH] |Male[MESH] |Muscles/drug effects/metabolism[MESH] |Potassium/*toxicity[MESH] |Rats[MESH] |Rats, Inbred Strains[MESH]Intracellular alkalosis induced by increasing extracellular potassium (epmc).pdf DeepDyve Pubget Overpricing