Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1016/j.chom.2012.04.009 http://scihub22266oqcxt.onion/10.1016/j.chom.2012.04.009 22607802!ä!22607802 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell+Host+Microbe 2012 ; 11 (5): 492-503 Nephropedia Template TP {{tp|p=22607802|t=2012. Bornavirus closely associates and segregates with host chromosomes to ensure persistent intranuclear infection |pdf=|usr=}}{{22607802}} gab.com Text Bornavirus closely associates and segregates with host chromosomes to ensure persistent intranuclear infection JO: Cell Host Microbe http://www.kidney.de/pget.php?&tw=1&pmid=22607802 #FOAvip Bornaviruses are nonsegmented negative-strand RNA viruses that establish a persistent infection in the nucleus and occasionally integrate a DNA genome copy into the host chromosomal DNA. However, how these viruses achieve intranuclear infection remains unclear. We show that Borna disease virus (BDV), a mammalian bornavirus, closely associates with the cellular chromosome to ensure intranuclear infection. BDV generates viral factories within the nucleus using host chromatin as a scaffold. In addition, the viral ribonucleoprotein (RNP) interacts directly with the host chromosome throughout the cell cycle, using core histones as a docking platform. HMGB1, a host chromatin-remodeling DNA architectural protein, is required to stabilize RNP on chromosomes and for efficient BDV RNA transcription in the nucleus. During metaphase, the association of RNP with mitotic chromosomes allows the viral RNA to segregate into daughter cells and ensure persistent infection. Thus, bornaviruses likely evolved a chromosome-dependent life cycle to achieve stable intranuclear infection. Twit Text FOAVip Bornavirus closely associates and segregates with host chromosomes to ensure persistent intranuclear infection ????Cell Host Microbe http://www.kidney.de/pget.php?&tw=1&pmid=22607802 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=22607802 #FOAvip English Wikipedia <ref>{{Cite pmid|22607802}}</ref> Bornavirus closely associates and segregates with host chromosomes to ensure persistent intranuclear infection #MMPMID22607802 Matsumoto Y; Hayashi Y; Omori H; Honda T; Daito T; Horie M; Ikuta K; Fujino K; Nakamura S; Schneider U; Chase G; Yoshimori T; Schwemmle M; Tomonaga K Cell Host Microbe 2012[May]; 11 (5): 492-503 PMID22607802show ga Bornaviruses are nonsegmented negative-strand RNA viruses that establish a persistent infection in the nucleus and occasionally integrate a DNA genome copy into the host chromosomal DNA. However, how these viruses achieve intranuclear infection remains unclear. We show that Borna disease virus (BDV), a mammalian bornavirus, closely associates with the cellular chromosome to ensure intranuclear infection. BDV generates viral factories within the nucleus using host chromatin as a scaffold. In addition, the viral ribonucleoprotein (RNP) interacts directly with the host chromosome throughout the cell cycle, using core histones as a docking platform. HMGB1, a host chromatin-remodeling DNA architectural protein, is required to stabilize RNP on chromosomes and for efficient BDV RNA transcription in the nucleus. During metaphase, the association of RNP with mitotic chromosomes allows the viral RNA to segregate into daughter cells and ensure persistent infection. Thus, bornaviruses likely evolved a chromosome-dependent life cycle to achieve stable intranuclear infection. |*Virus Replication[MESH] |Borna disease virus/*pathogenicity/*physiology[MESH] |Cell Cycle[MESH] |Cell Line[MESH] |Cell Nucleus/*virology[MESH] |Chromosome Segregation[MESH] |HMGB1 Protein/metabolism[MESH] |Histones/metabolism[MESH] |Host-Pathogen Interactions[MESH] |Humans[MESH] |Nucleoproteins/metabolism[MESH] |Protein Binding[MESH] |RNA, Viral/metabolism[MESH] |Transcription, Genetic[MESH]Bornavirus closely associates and segregates with host chromosomes to (epmc).pdf DeepDyve Pubget Overpricing