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10.2337/dc12-0226 http://scihub22266oqcxt.onion/10.2337/dc12-0226 22498805!3379604!22498805     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Diabetes+Care 2012 ; 35 (7): 1591-7 Nephropedia Template TP {{tp|p=22498805|t=2012. Hypomagnesemia in type 2 diabetic nephropathy: a novel predictor of end-stage renal disease |pdf=|usr=}}{{22498805}} gab.com Text Hypomagnesemia in type 2 diabetic nephropathy: a novel predictor of end-stage renal disease JO: Diabetes Care http://www.kidney.de/pget.php?&tw=1&pmid=22498805 #FOAvip OBJECTIVE: There is now growing evidence that magnesium (Mg) deficiency is implicated in type 2 diabetes and its complications. However, it has not been fully elucidated whether hypomagnesemia is a predictor of end-stage renal disease (ESRD) in type 2 diabetic nephropathy. RESEARCH DESIGN AND METHODS: This retrospective cohort study included 455 chronic kidney disease (CKD) patients (144 with type 2 diabetic nephropathy and 311 with nondiabetic CKD) who were hospitalized at Osaka General Medical Center for a CKD educational program between April 2001 and December 2007. The primary outcome was progression to renal replacement therapy. Participants were categorized based on serum Mg level into Low-Mg (serum Mg level </=1.8 mg/dL) and High-Mg (serum Mg level >1.8 mg/dL) groups with the previously published normal lower limit chosen as the cutoff point. RESULTS: Of the subjects with type 2 diabetic nephropathy, 102 progressed to ESRD during follow-up (median, 23 months). A multivariate Cox proportional hazards model showed that after adjustment for various demographic factors and laboratory data, the Low-Mg group had a 2.12-fold higher risk of ESRD than the High-Mg group (95% CI 1.28-3.51; P = 0.004). In contrast, 135 of the nondiabetic CKD subjects progressed to ESRD during follow-up (median, 44 months). No significant difference in outcome was found between the Low- and High-Mg groups of this population (adjusted hazard ratio, 1.15; 95% CI 0.70-1.90; P = 0.57). CONCLUSIONS: Hypomagnesemia is a novel predictor of ESRD in patients with type 2 diabetic nephropathy. Twit Text FOAVip Hypomagnesemia in type 2 diabetic nephropathy: a novel predictor of end-stage renal disease ????Diabetes Care http://www.kidney.de/pget.php?&tw=1&pmid=22498805 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=22498805 #FOAvip English Wikipedia <ref>{{Cite pmid|22498805}}</ref> Hypomagnesemia in type 2 diabetic nephropathy: a novel predictor of end-stage renal disease #MMPMID22498805 Sakaguchi Y; Shoji T; Hayashi T; Suzuki A; Shimizu M; Mitsumoto K; Kawabata H; Niihata K; Okada N; Isaka Y; Rakugi H; Tsubakihara Y Diabetes Care 2012[Jul]; 35 (7): 1591-7 PMID22498805show ga OBJECTIVE: There is now growing evidence that magnesium (Mg) deficiency is implicated in type 2 diabetes and its complications. However, it has not been fully elucidated whether hypomagnesemia is a predictor of end-stage renal disease (ESRD) in type 2 diabetic nephropathy. RESEARCH DESIGN AND METHODS: This retrospective cohort study included 455 chronic kidney disease (CKD) patients (144 with type 2 diabetic nephropathy and 311 with nondiabetic CKD) who were hospitalized at Osaka General Medical Center for a CKD educational program between April 2001 and December 2007. The primary outcome was progression to renal replacement therapy. Participants were categorized based on serum Mg level into Low-Mg (serum Mg level 1.8 mg/dL) groups with the previously published normal lower limit chosen as the cutoff point. RESULTS: Of the subjects with type 2 diabetic nephropathy, 102 progressed to ESRD during follow-up (median, 23 months). A multivariate Cox proportional hazards model showed that after adjustment for various demographic factors and laboratory data, the Low-Mg group had a 2.12-fold higher risk of ESRD than the High-Mg group (95% CI 1.28-3.51; P = 0.004). In contrast, 135 of the nondiabetic CKD subjects progressed to ESRD during follow-up (median, 44 months). No significant difference in outcome was found between the Low- and High-Mg groups of this population (adjusted hazard ratio, 1.15; 95% CI 0.70-1.90; P = 0.57). CONCLUSIONS: Hypomagnesemia is a novel predictor of ESRD in patients with type 2 diabetic nephropathy. |Aged[MESH] |Cohort Studies[MESH] |Diabetes Mellitus, Type 2/*complications[MESH] |Diabetic Nephropathies/*complications[MESH] |Disease Progression[MESH] |Female[MESH] |Humans[MESH] |Kidney Failure, Chronic/*etiology[MESH] |Magnesium Deficiency/*complications[MESH] |Magnesium/*blood[MESH] |Male[MESH] |Middle Aged[MESH] |Renal Insufficiency, Chronic/complications[MESH] |Retrospective Studies[MESH]Hypomagnesemia in type 2 diabetic nephropathy: a novel predictor of en(epmc).pdf DeepDyve Pubget Overpricing