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10.1016/j.bmcl.2012.02.105 http://scihub22266oqcxt.onion/10.1016/j.bmcl.2012.02.105 22446091!7126871!22446091     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 269.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Bioorg+Med+Chem+Lett 2012 ; 22 (8): 2705-7 Nephropedia Template TP {{tp|p=22446091|t=2012. Synthesis and antiviral activity of a series of 1 -substituted 4-aza-7,9-dideazaadenosine C-nucleosides |pdf=|usr=}}{{22446091}} gab.com Text Synthesis and antiviral activity of a series of 1 -substituted 4-aza-7,9-dideazaadenosine C-nucleosides JO: Bioorg Med Chem Lett http://www.kidney.de/pget.php?&tw=1&pmid=22446091 #FOAvip A series of 1'-substituted analogs of 4-aza-7,9-dideazaadenosine C-nucleoside were prepared and evaluated for the potential as antiviral agents. These compounds showed a broad range of inhibitory activity against various RNA viruses. In particular, the whole cell potency against HCV when R=CN was attributed to inhibition of HCV NS5B polymerase and intracellular concentration of the corresponding nucleoside triphosphate. Twit Text FOAVip Synthesis and antiviral activity of a series of 1 -substituted 4-aza-7,9-dideazaadenosine C-nucleosides ????Bioorg Med Chem Lett http://www.kidney.de/pget.php?&tw=1&pmid=22446091 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=22446091 #FOAvip English Wikipedia <ref>{{Cite pmid|22446091}}</ref> Synthesis and antiviral activity of a series of 1 -substituted 4-aza-7,9-dideazaadenosine C-nucleosides #MMPMID22446091 Cho A; Saunders OL; Butler T; Zhang L; Xu J; Vela JE; Feng JY; Ray AS; Kim CU Bioorg Med Chem Lett 2012[Apr]; 22 (8): 2705-7 PMID22446091show ga A series of 1'-substituted analogs of 4-aza-7,9-dideazaadenosine C-nucleoside were prepared and evaluated for the potential as antiviral agents. These compounds showed a broad range of inhibitory activity against various RNA viruses. In particular, the whole cell potency against HCV when R=CN was attributed to inhibition of HCV NS5B polymerase and intracellular concentration of the corresponding nucleoside triphosphate. |Adenosine/chemical synthesis/chemistry/pharmacology[MESH] |Antiviral Agents/*chemical synthesis/chemistry/*pharmacology[MESH] |Aza Compounds/chemical synthesis/chemistry/pharmacology[MESH] |Hepacivirus/*drug effects[MESH] |Humans[MESH] |Molecular Structure[MESH] |Nucleosides/*chemical synthesis/chemistry/*pharmacology[MESH]Synthesis and antiviral activity of a series of 1 -substituted 4-aza-(epmc).pdf DeepDyve Pubget Overpricing