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http://scihub22266oqcxt.onion/ 22311354!ä!22311354 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Hong+Kong+Med+J 2012 ; 18 Suppl 2 (ä): 12-6 Nephropedia Template TP {{tp|p=22311354|t=2012. Interferon dysregulation and virus-induced cell death in avian influenza H5N1 virus infections |pdf=|usr=}}{{22311354}} gab.com Text Interferon dysregulation and virus-induced cell death in avian influenza H5N1 virus infections JO: Hong Kong Med J http://www.kidney.de/pget.php?&tw=1&pmid=22311354 #FOAvip 1. Hyper-induction of cytokines and chemokines was found in human blood macrophages infected with the avian influenza H5N1 and H9N2/G1 viruses, as compared to those infected with human influenza H1N1 virus. 2. IRF3 played a significant role in the hyperinduction of cytokines including IFN-beta, IFN-lambda1,IFN-alpha subtypes, MCP-1, and TNF-alpha, and also played a part in subsequent cytokine-induced cell signalling cascades. 3. Compared with H1N1 viruses, avian influenza viruses including H5N1/97 and its precursors triggered a caspase-mediated but delayed apoptotic response in human macrophages. 4. Therapies that can minimise immunopathology-associated dysregulation of innate immunity without impairing effective host defence may be valuable adjuncts to antiviral therapy. Twit Text FOAVip Interferon dysregulation and virus-induced cell death in avian influenza H5N1 virus infections ????Hong Kong Med J http://www.kidney.de/pget.php?&tw=1&pmid=22311354 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=22311354 #FOAvip English Wikipedia <ref>{{Cite pmid|22311354}}</ref> Interferon dysregulation and virus-induced cell death in avian influenza H5N1 virus infections #MMPMID22311354 Lee DC; Law AH; Hui K; Tam AH; Peiris JS; Lau AS Hong Kong Med J 2012[Feb]; 18 Suppl 2 (ä): 12-6 PMID22311354show ga 1. Hyper-induction of cytokines and chemokines was found in human blood macrophages infected with the avian influenza H5N1 and H9N2/G1 viruses, as compared to those infected with human influenza H1N1 virus. 2. IRF3 played a significant role in the hyperinduction of cytokines including IFN-beta, IFN-lambda1,IFN-alpha subtypes, MCP-1, and TNF-alpha, and also played a part in subsequent cytokine-induced cell signalling cascades. 3. Compared with H1N1 viruses, avian influenza viruses including H5N1/97 and its precursors triggered a caspase-mediated but delayed apoptotic response in human macrophages. 4. Therapies that can minimise immunopathology-associated dysregulation of innate immunity without impairing effective host defence may be valuable adjuncts to antiviral therapy. |*Apoptosis[MESH] |*Influenza A Virus, H5N1 Subtype[MESH] |Caspase 3/metabolism[MESH] |Cells, Cultured[MESH] |Cytokines/biosynthesis/*genetics[MESH] |Gene Expression Regulation[MESH] |Humans[MESH] |Influenza A Virus, H1N1 Subtype[MESH] |Influenza, Human/*metabolism[MESH] |Interferon Regulatory Factor-3/genetics/*metabolism[MESH] |Interferon-beta/biosynthesis/genetics[MESH] |Interferons[MESH] |Interleukins/biosynthesis/genetics[MESH] |Macrophages/enzymology/*metabolism/virology[MESH] |Poly(ADP-ribose) Polymerases/metabolism[MESH] |RNA, Messenger/*metabolism[MESH] |RNA, Small Interfering[MESH] |Transcription Factors/metabolism[MESH] |Tumor Necrosis Factor-alpha/biosynthesis/genetics[MESH]Interferon dysregulation and virus-induced cell death in avian influen(epmc).pdf DeepDyve Pubget Overpricing