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10.1371/journal.pone.0029474 http://scihub22266oqcxt.onion/10.1371/journal.pone.0029474 22235298!3250454!22235298     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       PLoS+One 2012 ; 7 (1): e29474 Nephropedia Template TP {{tp|p=22235298|t=2012. High prevalence of human parvovirus 4 infection in HBV and HCV infected individuals in shanghai |pdf=|usr=}}{{22235298}} gab.com Text High prevalence of human parvovirus 4 infection in HBV and HCV infected individuals in shanghai JO: PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=22235298 #FOAvip Human parvovirus 4 (PARV4) has been detected in blood and diverse tissues samples from HIV/AIDS patients who are injecting drug users. Although B19 virus, the best characterized human parvovirus, has been shown to co-infect patients with hepatitis B or hepatitis C virus (HBV, HCV) infection, the association of PARV4 with HBV or HCV infections is still unknown.The aim of this study was to characterise the association of viruses belonging to PARV4 genotype 1 and 2 with chronic HBV and HCV infection in Shanghai.Serum samples of healthy controls, HCV infected subjects and HBV infected subjects were retrieved from Shanghai Center for Disease Control and Prevention (SCDC) Sample Bank. Parvovirus-specific nested-PCR was performed and results confirmed by sequencing. Sequences were compared with reference sequences obtained from Genbank to derive phylogeny trees.The frequency of parvovirus molecular detection was 16-22%, 33% and 41% in healthy controls, HCV infected and HBV infected subjects respectively, with PARV4 being the only parvovirus detected. HCV infected and HBV infected subjects had a significantly higher PARV4 prevalence than the healthy population. No statistical difference was found in PARV4 prevalence between HBV or HCV infected subjects. PARV4 sequence divergence within study groups was similar in healthy subjects, HBV or HCV infected subjects.Our data clearly demonstrate that PARV4 infection is strongly associated with HCV and HBV infection in Shanghai but may not cause increased disease severity. Twit Text FOAVip High prevalence of human parvovirus 4 infection in HBV and HCV infected individuals in shanghai ????PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=22235298 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=22235298 #FOAvip English Wikipedia <ref>{{Cite pmid|22235298}}</ref> High prevalence of human parvovirus 4 infection in HBV and HCV infected individuals in shanghai #MMPMID22235298 Yu X; Zhang J; Hong L; Wang J; Yuan Z; Zhang X; Ghildyal R PLoS One 2012[]; 7 (1): e29474 PMID22235298show ga Human parvovirus 4 (PARV4) has been detected in blood and diverse tissues samples from HIV/AIDS patients who are injecting drug users. Although B19 virus, the best characterized human parvovirus, has been shown to co-infect patients with hepatitis B or hepatitis C virus (HBV, HCV) infection, the association of PARV4 with HBV or HCV infections is still unknown.The aim of this study was to characterise the association of viruses belonging to PARV4 genotype 1 and 2 with chronic HBV and HCV infection in Shanghai.Serum samples of healthy controls, HCV infected subjects and HBV infected subjects were retrieved from Shanghai Center for Disease Control and Prevention (SCDC) Sample Bank. Parvovirus-specific nested-PCR was performed and results confirmed by sequencing. Sequences were compared with reference sequences obtained from Genbank to derive phylogeny trees.The frequency of parvovirus molecular detection was 16-22%, 33% and 41% in healthy controls, HCV infected and HBV infected subjects respectively, with PARV4 being the only parvovirus detected. HCV infected and HBV infected subjects had a significantly higher PARV4 prevalence than the healthy population. No statistical difference was found in PARV4 prevalence between HBV or HCV infected subjects. PARV4 sequence divergence within study groups was similar in healthy subjects, HBV or HCV infected subjects.Our data clearly demonstrate that PARV4 infection is strongly associated with HCV and HBV infection in Shanghai but may not cause increased disease severity. |Adult[MESH] |Case-Control Studies[MESH] |China/epidemiology[MESH] |DNA, Viral/blood[MESH] |Female[MESH] |Genotype[MESH] |Hepatitis B/*complications[MESH] |Hepatitis C/*complications[MESH] |Humans[MESH] |Male[MESH] |Middle Aged[MESH] |Parvoviridae Infections/blood/*complications/*epidemiology/virology[MESH] |Parvovirus/genetics/*pathogenicity[MESH] |Prevalence[MESH] |Real-Time Polymerase Chain Reaction[MESH] |Sequence Homology, Nucleic Acid[MESH]High prevalence of human parvovirus 4 infection in HBV and HCV infecte(epmc).pdf DeepDyve Pubget Overpricing