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  • Novel modifications in RNA #MMPMID22148740
  • Phelps K; Morris A; Beal PA
  • ACS Chem Biol 2012[Jan]; 7 (1): 100-9 PMID22148740garesp_yesshow ga
  • The past several years have seen numerous reports of new chemical modifications for use in RNA. In addition, in that time period, we have seen the discovery of several previously unknown naturally occurring modifications that impart novel properties on the parent RNAs. In this review, we describe recent discoveries in these areas with a focus on RNA modifications that introduce spectroscopic tags, reactive handles, or new recognition properties.
  • |Alkynes/chemistry/metabolism[MESH]
  • |Azides/chemistry/metabolism[MESH]
  • |Binding Sites[MESH]
  • |Click Chemistry/*methods[MESH]
  • |Drug Design[MESH]
  • |Fluorescent Dyes/*chemistry/metabolism[MESH]
  • |Free Radicals/chemistry/metabolism[MESH]
  • |Humans[MESH]
  • |Inverted Repeat Sequences[MESH]
  • |Magnetic Resonance Spectroscopy[MESH]
  • |Molecular Probes/*chemistry/metabolism[MESH]
  • |Molecular Sequence Data[MESH]
  • |Nucleosides/chemistry/metabolism[MESH]
  • |Nucleotide Motifs/*genetics[MESH]
  • |RNA, Small Interfering/*chemistry/metabolism[MESH]
  • |Spectrometry, Fluorescence[MESH]
  • |Toluene/analogs & derivatives/chemistry/metabolism[MESH]

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    100 1.7 2012