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10.1007/s10753-011-9399-0 http://scihub22266oqcxt.onion/10.1007/s10753-011-9399-0 22038065!ä!22038065 Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=22038065&cmd=llinks): Failed to open stream: HTTP request failed! 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Chlorophyll revisited: anti-inflammatory activities of chlorophyll a and inhibition of expression of TNF-alpha gene by the same |pdf=|usr=}}{{22038065}} gab.com Text Chlorophyll revisited: anti-inflammatory activities of chlorophyll a and inhibition of expression of TNF-alpha gene by the same JO: Inflammation http://www.kidney.de/pget.php?&tw=1&pmid=22038065 #FOAvip In view of the folklore use of green leaves to treat inflammation, the anti-inflammatory property of chlorophylls and their degradation products were studied. Chlorophyll a and pheophytin a (magnesium-free chlorophyll a) from fresh leaves showed potent anti-inflammatory activity against carrageenan-induced paw edema in mice and formalin-induced paw edema in rats. Chlorophyll a inhibited bacterial lipopolysaccharide-induced TNF-alpha (a pro-inflammatory cytokine) gene expression in HEK293 cells, but it did not influence the expression of inducible nitric acid synthase and cyclooxygenase-2 genes. Chlorophyll b only marginally inhibited both inflammation and TNF-alpha gene expression. But both chlorophyll a and chlorophyll b showed the same level of marginal inhibition on 12-O-tetradecanoyl-phorbol-13-acetate-induced NF-kappaB activation. Chlorophylls and pheophytins showed in vitro anti-oxidant activity. The study shows that chlorophyll a and its degradation products are valuable and abundantly available anti-inflammatory agents and promising for the development of phytomedicine or conventional medicine to treat inflammation and related diseases. Twit Text FOAVip Chlorophyll revisited: anti-inflammatory activities of chlorophyll a and inhibition of expression of TNF-alpha gene by the same ????Inflammation http://www.kidney.de/pget.php?&tw=1&pmid=22038065 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=22038065 #FOAvip English Wikipedia <ref>{{Cite pmid|22038065}}</ref> Chlorophyll revisited: anti-inflammatory activities of chlorophyll a and inhibition of expression of TNF-alpha gene by the same #MMPMID22038065 Subramoniam A; Asha VV; Nair SA; Sasidharan SP; Sureshkumar PK; Rajendran KN; Karunagaran D; Ramalingam K Inflammation 2012[Jun]; 35 (3): 959-66 PMID22038065show ga In view of the folklore use of green leaves to treat inflammation, the anti-inflammatory property of chlorophylls and their degradation products were studied. Chlorophyll a and pheophytin a (magnesium-free chlorophyll a) from fresh leaves showed potent anti-inflammatory activity against carrageenan-induced paw edema in mice and formalin-induced paw edema in rats. Chlorophyll a inhibited bacterial lipopolysaccharide-induced TNF-alpha (a pro-inflammatory cytokine) gene expression in HEK293 cells, but it did not influence the expression of inducible nitric acid synthase and cyclooxygenase-2 genes. Chlorophyll b only marginally inhibited both inflammation and TNF-alpha gene expression. But both chlorophyll a and chlorophyll b showed the same level of marginal inhibition on 12-O-tetradecanoyl-phorbol-13-acetate-induced NF-kappaB activation. Chlorophylls and pheophytins showed in vitro anti-oxidant activity. The study shows that chlorophyll a and its degradation products are valuable and abundantly available anti-inflammatory agents and promising for the development of phytomedicine or conventional medicine to treat inflammation and related diseases. |Animals[MESH] |Anti-Inflammatory Agents, Non-Steroidal/*pharmacology/therapeutic use[MESH] |Carrageenan[MESH] |Chlorophyll A[MESH] |Chlorophyll/*pharmacology/therapeutic use[MESH] |Chromolaena[MESH] |Cyclooxygenase 2/metabolism[MESH] |Edema/drug therapy[MESH] |Eupatorium[MESH] |Formaldehyde[MESH] |HEK293 Cells[MESH] |Humans[MESH] |Inflammation/*drug therapy[MESH] |Lipopolysaccharides/immunology[MESH] |Mice[MESH] |Moraceae[MESH] |NF-kappa B/biosynthesis[MESH] |Nitric Oxide Synthase Type II/metabolism[MESH] |Pheophytins/*pharmacology/therapeutic use[MESH] |Plant Extracts/*pharmacology/therapeutic use[MESH] |Rats[MESH] |Rats, Wistar[MESH] |Tetradecanoylphorbol Acetate/pharmacology[MESH]Chlorophyll revisited: anti-inflammatory activities of chlorophyll a a(epmc).pdf DeepDyve Pubget Overpricing