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10.1111/j.1399-3046.2011.01570.x http://scihub22266oqcxt.onion/10.1111/j.1399-3046.2011.01570.x 22032720!ä!22032720 Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=22032720&cmd=llinks): Failed to open stream: HTTP request failed! 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Castleman disease in a pediatric liver transplant recipient: a case report and literature review |pdf=|usr=}}{{22032720}} gab.com Text Castleman disease in a pediatric liver transplant recipient: a case report and literature review JO: Pediatr Transplant http://www.kidney.de/pget.php?&tw=1&pmid=22032720 #FOAvip Castleman disease is a rare hematologic disorder, closely linked to the HHV-8, and most commonly observed in immunocompromised individuals. Thirteen months following a liver transplant for CPS-1 defect, a 15-month-old boy presented with fevers, anemia, and growth retardation. Abdominal CT scan showed splenomegaly and generalized lymphadenopathy. Histology of chest wall lymph nodes revealed a mixed CD3+ T-cell and CD20+ B-cell population with atretic germinal centers consistent with multicentric Castleman disease. Qualitative DNA PCR detected HHV-8 in the resected lymph node and in the blood, supporting the diagnosis. Immunosuppression was tapered, and he was transitioned from tacrolimus to sirolimus. His graft function remained stable, and repeat imaging showed regression of the lymphadenopathy. The child is living one yr after Castleman disease diagnosis with a well-functioning graft. Castleman disease is a potential complication of solid organ transplant and HHV-8 infection. Reduction in immunosuppression and switch to sirolimus may be an effective strategy to treat this condition. Twit Text FOAVip Castleman disease in a pediatric liver transplant recipient: a case report and literature review ????Pediatr Transplant http://www.kidney.de/pget.php?&tw=1&pmid=22032720 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=22032720 #FOAvip English Wikipedia <ref>{{Cite pmid|22032720}}</ref> Castleman disease in a pediatric liver transplant recipient: a case report and literature review #MMPMID22032720 Bonatti HJ; Axt J; Hunter EB; Lott SL; Frangoul H; Gillis L; Correa H; Kelly B Pediatr Transplant 2012[Sep]; 16 (6): E229-34 PMID22032720show ga Castleman disease is a rare hematologic disorder, closely linked to the HHV-8, and most commonly observed in immunocompromised individuals. Thirteen months following a liver transplant for CPS-1 defect, a 15-month-old boy presented with fevers, anemia, and growth retardation. Abdominal CT scan showed splenomegaly and generalized lymphadenopathy. Histology of chest wall lymph nodes revealed a mixed CD3+ T-cell and CD20+ B-cell population with atretic germinal centers consistent with multicentric Castleman disease. Qualitative DNA PCR detected HHV-8 in the resected lymph node and in the blood, supporting the diagnosis. Immunosuppression was tapered, and he was transitioned from tacrolimus to sirolimus. His graft function remained stable, and repeat imaging showed regression of the lymphadenopathy. The child is living one yr after Castleman disease diagnosis with a well-functioning graft. Castleman disease is a potential complication of solid organ transplant and HHV-8 infection. Reduction in immunosuppression and switch to sirolimus may be an effective strategy to treat this condition. |Adolescent[MESH] |Adult[MESH] |Antigens, CD20/biosynthesis[MESH] |B-Lymphocytes/metabolism[MESH] |CD3 Complex/biosynthesis[MESH] |Castleman Disease/*complications/diagnosis[MESH] |Graft Survival[MESH] |Herpesvirus 8, Human/genetics[MESH] |Humans[MESH] |Immunosuppressive Agents/therapeutic use[MESH] |Infant, Newborn[MESH] |Liver Failure/*complications/*therapy[MESH] |Liver Transplantation/adverse effects/*methods[MESH] |Lymphatic Diseases/diagnosis[MESH] |Male[MESH] |Middle Aged[MESH] |Polymerase Chain Reaction[MESH] |Sirolimus/administration & dosage[MESH] |Splenomegaly/diagnosis[MESH] |T-Lymphocytes/metabolism[MESH] |Tacrolimus/administration & dosage[MESH]Castleman disease in a pediatric liver transplant recipient: a case re(epmc).pdf DeepDyve Pubget Overpricing