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10.1002/ppul.21552 http://scihub22266oqcxt.onion/10.1002/ppul.21552 21901859!7168072!21901859     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Pediatr+Pulmonol 2012 ; 47 (4): 393-400 Nephropedia Template TP {{tp|p=21901859|t=2012. Infection with multiple viruses is not associated with increased disease severity in children with bronchiolitis |pdf=|usr=}}{{21901859}} gab.com Text Infection with multiple viruses is not associated with increased disease severity in children with bronchiolitis JO: Pediatr Pulmonol http://www.kidney.de/pget.php?&tw=1&pmid=21901859 #FOAvip BACKGROUND: The clinical relevance of parallel detection of multiple viruses by real-time polymerase chain reaction (RT-PCR) remains unclear. This study evaluated the association between the detection of multiple viruses by RT-PCR and disease severity in children with bronchiolitis. METHODS: Children less than 2 years of age with clinical symptoms of bronchiolitis were prospectively included during three winter seasons. Patients were categorized in three groups based on disease severity; mild (no supportive treatment), moderate (supplemental oxygen and/or nasogastric feeding), and severe (mechanical ventilation). Multiplex RT-PCR of 15 respiratory viruses was performed on nasopharyngeal aspirates. RESULTS: In total, 142 samples were obtained. Respiratory Syncytial virus (RSV) was the most commonly detected virus (73%) followed by rhinovirus (RV) (30%). In 58 samples (41%) more than one virus was detected, of which 41% was a dual infection with RSV and RV. In RSV infected children younger than 3 months, disease severity was not associated with the number of detected viruses. Remarkably, in children older than 3 months we found an association between more severe disease and RSV mono-infections. CONCLUSION: Disease severity in children with bronchiolitis is not associated with infection by multiple viruses. We conclude that other factors, such as age, contribute to disease severity to a larger extent. Twit Text FOAVip Infection with multiple viruses is not associated with increased disease severity in children with bronchiolitis ????Pediatr Pulmonol http://www.kidney.de/pget.php?&tw=1&pmid=21901859 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=21901859 #FOAvip English Wikipedia <ref>{{Cite pmid|21901859}}</ref> Infection with multiple viruses is not associated with increased disease severity in children with bronchiolitis #MMPMID21901859 Brand HK; de Groot R; Galama JM; Brouwer ML; Teuwen K; Hermans PW; Melchers WJ; Warris A Pediatr Pulmonol 2012[Apr]; 47 (4): 393-400 PMID21901859show ga BACKGROUND: The clinical relevance of parallel detection of multiple viruses by real-time polymerase chain reaction (RT-PCR) remains unclear. This study evaluated the association between the detection of multiple viruses by RT-PCR and disease severity in children with bronchiolitis. METHODS: Children less than 2 years of age with clinical symptoms of bronchiolitis were prospectively included during three winter seasons. Patients were categorized in three groups based on disease severity; mild (no supportive treatment), moderate (supplemental oxygen and/or nasogastric feeding), and severe (mechanical ventilation). Multiplex RT-PCR of 15 respiratory viruses was performed on nasopharyngeal aspirates. RESULTS: In total, 142 samples were obtained. Respiratory Syncytial virus (RSV) was the most commonly detected virus (73%) followed by rhinovirus (RV) (30%). In 58 samples (41%) more than one virus was detected, of which 41% was a dual infection with RSV and RV. In RSV infected children younger than 3 months, disease severity was not associated with the number of detected viruses. Remarkably, in children older than 3 months we found an association between more severe disease and RSV mono-infections. CONCLUSION: Disease severity in children with bronchiolitis is not associated with infection by multiple viruses. We conclude that other factors, such as age, contribute to disease severity to a larger extent. |Bronchiolitis/*virology[MESH] |Female[MESH] |Humans[MESH] |Infant[MESH] |Male[MESH] |Picornaviridae Infections/*diagnosis/virology[MESH] |Prospective Studies[MESH] |Respiratory Syncytial Virus Infections/*diagnosis/virology[MESH] |Reverse Transcriptase Polymerase Chain Reaction[MESH] |Rhinovirus/isolation & purification[MESH]Infection with multiple viruses is not associated with increased disea(epmc).pdf DeepDyve Pubget Overpricing