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10.1155/2011/718609

http://scihub22266oqcxt.onion/10.1155/2011/718609
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21808734!3144718!21808734
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suck abstract from ncbi

pmid21808734      J+Signal+Transduct 2011 ; 2011 (?): 718609
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  • Relevance of VEGF and nephrin expression in glomerular diseases #MMPMID21808734
  • Bertuccio CA
  • J Signal Transduct 2011[]; 2011 (?): 718609 PMID21808734show ga
  • The glomerular filtration barrier is affected in a large number of acquired and inherited diseases resulting in extensive leakage of plasma albumin and larger proteins, leading to nephrotic syndrome and end-stage renal disease. Unfortunately, the molecular mechanisms governing the development of the nephrotic syndrome remain poorly understood. Here, I give an overview of recent investigations that have focused on characterizing the interrelationships between the slit diaphragm components and podocytes-secreted VEGF, which have a significant role for maintaining the normal podocyte structure and the integrity of the filtering barrier.
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