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suck abstract from ncbi


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pmid21751692      AANA+J 2011 ; 79 (3): 238-42
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  • Prevention of emergence agitation in seven children receiving low-dose ketamine and propofol total intravenous anesthesia #MMPMID21751692
  • Anghelescu DL; Rakes LC; Shearer JR; Bikhazi GB
  • AANA J 2011[Jun]; 79 (3): 238-42 PMID21751692show ga
  • Emergence agitation (EA) can be a distressing side effect of pediatric anesthesia. We retrospectively reviewed the records of 7 pediatric oncology patients who received low-dose ketamine in conjunction with propofol for total intravenous anesthesia (TIVA) repeatedly for radiation therapy. EA signs were observed in all 7 patients in association with propofol TIVA but did not recur in any of 123 subsequent anesthetics sessions during which low-dose ketamine was added to propofol. Based on this experience, we suggest that low-dose ketamine added to propofol may be associated with prevention of EA in children with a history of EA with propofol TIVA.
  • |Anesthetics, Dissociative/*administration & dosage[MESH]
  • |Anesthetics, Intravenous/administration & dosage/*adverse effects[MESH]
  • |Child, Preschool[MESH]
  • |Drug Interactions[MESH]
  • |Humans[MESH]
  • |Infant[MESH]
  • |Ketamine/*administration & dosage[MESH]
  • |Neoplasms/radiotherapy[MESH]
  • |Postoperative Complications/*prevention & control[MESH]
  • |Propofol/administration & dosage/*adverse effects[MESH]
  • |Psychomotor Agitation/*prevention & control[MESH]


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