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10.1097/00000658-199004000-00015 http://scihub22266oqcxt.onion/10.1097/00000658-199004000-00015 2157378Preoperativechemotherapyforsoft-tissuesarcomasoftheextremities.!1358035!2157378     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Ann+Surg 1990 ; 211 (4): 476-81 Nephropedia Template TP {{tp|p=2157378|t=1990. Preoperative chemotherapy for soft-tissue sarcomas of the extremities |pdf=|usr=}}{{2157378}} gab.com Text Preoperative chemotherapy for soft-tissue sarcomas of the extremities JO: Ann Surg http://www.kidney.de/pget.php?&tw=1&pmid=2157378 #FOAvip Forty-six patients with extremity soft-tissue sarcomas were treated with a mean of 4.4 cycles of preoperative adriamycin-based combination chemotherapy, followed by definitive local surgery and radiotherapy. All tumors were larger than 5 cm and of histologic type having significant risk of metastasis. Eighteen patients (40%) had an objective clinical response to the chemotherapy, while 27 patients (60%) did not respond. Patients with tumors responsive to chemotherapy had significantly improved overall survival (median 60 + months versus 32.7 months; p = 0.02), continuous disease-free survival (median 60 + months versus 15.1 months; p = 0.04), and distant metastasis-free survival (median 60+ months versus 28.5 months; p = 0.006) compared to the nonresponding patients. Tumor response to preoperative chemotherapy provides strong prognostic information and identifies a subgroup of patients most likely to benefit from chemotherapy. Twit Text FOAVip Preoperative chemotherapy for soft-tissue sarcomas of the extremities ????Ann Surg http://www.kidney.de/pget.php?&tw=1&pmid=2157378 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=2157378 #FOAvip English Wikipedia <ref>{{Cite pmid|2157378}}</ref> Preoperative chemotherapy for soft-tissue sarcomas of the extremities #MMPMID2157378 Pezzi CM; Pollock RE; Evans HL; Lorigan JG; Pezzi TA; Benjamin RS; Romsdahl MM Ann Surg 1990[Apr]; 211 (4): 476-81 PMID2157378show ga Forty-six patients with extremity soft-tissue sarcomas were treated with a mean of 4.4 cycles of preoperative adriamycin-based combination chemotherapy, followed by definitive local surgery and radiotherapy. All tumors were larger than 5 cm and of histologic type having significant risk of metastasis. Eighteen patients (40%) had an objective clinical response to the chemotherapy, while 27 patients (60%) did not respond. Patients with tumors responsive to chemotherapy had significantly improved overall survival (median 60 + months versus 32.7 months; p = 0.02), continuous disease-free survival (median 60 + months versus 15.1 months; p = 0.04), and distant metastasis-free survival (median 60+ months versus 28.5 months; p = 0.006) compared to the nonresponding patients. Tumor response to preoperative chemotherapy provides strong prognostic information and identifies a subgroup of patients most likely to benefit from chemotherapy. |Antineoplastic Combined Chemotherapy Protocols/*therapeutic use[MESH] |Cyclophosphamide/administration & dosage[MESH] |Dacarbazine/administration & dosage[MESH] |Doxorubicin/administration & dosage[MESH] |Extremities[MESH] |Female[MESH] |Histiocytoma, Benign Fibrous/*drug therapy/mortality/surgery[MESH] |Humans[MESH] |Male[MESH] |Preoperative Care[MESH] |Retrospective Studies[MESH] |Sarcoma/*drug therapy/mortality/surgery[MESH] |Soft Tissue Neoplasms/*drug therapy/mortality/surgery[MESH]Preoperative chemotherapy for soft-tissue sarcomas of the extremities (epmc).pdf DeepDyve Pubget Overpricing