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10.1016/j.hrtlng.2010.12.008 http://scihub22266oqcxt.onion/10.1016/j.hrtlng.2010.12.008 21411146!ä!21411146 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Heart+Lung 2011 ; 40 (5): 448-53 Nephropedia Template TP {{tp|p=21411146|t=2011. Methadone-induced torsades de pointes: a twist of fate |pdf=|usr=}}{{21411146}} gab.com Text Methadone-induced torsades de pointes: a twist of fate JO: Heart Lung http://www.kidney.de/pget.php?&tw=1&pmid=21411146 #FOAvip A case of methadone-induced torsades de pointes is presented to demonstrate clinical features that predispose patients to this serious cardiac arrhythmia. A patient who was receiving methadone maintenance treatment for heroin addiction presented to the hospital with dizziness and near-syncope. He was taking a relatively high dose of methadone but was not taking any concomitant cytochrome P450 inhibitor or QT-prolonging drugs. He had prolonged corrected QT interval, hypokalemia, and hypomagnesemia on admission and was later found to have severe left ventricular dysfunction. On admission to a telemetry unit, the patient experienced chest discomfort and palpitations with corresponding torsades de pointes that was terminated with correction of hypokalemia and hypomagnesemia. The corrected QT interval became shorter but remained profoundly prolonged until methadone was substituted with buprenorphine. Twit Text FOAVip Methadone-induced torsades de pointes: a twist of fate ????Heart Lung http://www.kidney.de/pget.php?&tw=1&pmid=21411146 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=21411146 #FOAvip English Wikipedia <ref>{{Cite pmid|21411146}}</ref> Methadone-induced torsades de pointes: a twist of fate #MMPMID21411146 Thanavaro KL; Thanavaro JL Heart Lung 2011[Sep]; 40 (5): 448-53 PMID21411146show ga A case of methadone-induced torsades de pointes is presented to demonstrate clinical features that predispose patients to this serious cardiac arrhythmia. A patient who was receiving methadone maintenance treatment for heroin addiction presented to the hospital with dizziness and near-syncope. He was taking a relatively high dose of methadone but was not taking any concomitant cytochrome P450 inhibitor or QT-prolonging drugs. He had prolonged corrected QT interval, hypokalemia, and hypomagnesemia on admission and was later found to have severe left ventricular dysfunction. On admission to a telemetry unit, the patient experienced chest discomfort and palpitations with corresponding torsades de pointes that was terminated with correction of hypokalemia and hypomagnesemia. The corrected QT interval became shorter but remained profoundly prolonged until methadone was substituted with buprenorphine. |Analgesics, Opioid/*adverse effects[MESH] |Heroin Dependence[MESH] |Humans[MESH] |Hypokalemia/chemically induced[MESH] |Magnesium Deficiency/chemically induced[MESH] |Male[MESH] |Methadone/*adverse effects[MESH] |Middle Aged[MESH] |Risk Factors[MESH] |Torsades de Pointes/*chemically induced[MESH]Methadone-induced torsades de pointes: a twist of fate (epmc).pdf DeepDyve Pubget Overpricing