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2130826!ä!2130826

suck abstract from ncbi


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pmid2130826      Magnes+Trace+Elem 1990 ; 9 (5): 279-82
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  • Na(+)-dependent Mg2+ efflux from Mg(2+)-loaded rat thymocytes and HL 60 cells #MMPMID2130826
  • Gunther T; Vormann J
  • Magnes Trace Elem 1990[]; 9 (5): 279-82 PMID2130826show ga
  • Mg(2+)-loaded rat thymocytes and HL 60 (human promyelocytic leukemia) cells expressed a high rate of Na(+)-dependent net Mg2+ efflux which was inhibited by two thirds by 1 mM amiloride. During net Mg2+ efflux, extracellular Na+ was taken up at a stoichiometric ratio of 2 Na+ to 1 Mg2+, indicating electroneutral Na+/Mg2+ antiport as found for erythrocytes. Na(+)-independent Mg2+ efflux was not significantly expressed in these cell types.
  • |Animals[MESH]
  • |Biological Transport, Active/drug effects[MESH]
  • |Cell Line[MESH]
  • |Humans[MESH]
  • |Leukemia, Myeloid/*metabolism/pathology[MESH]
  • |Magnesium/*metabolism/pharmacology[MESH]
  • |Rats[MESH]
  • |Rats, Inbred Strains[MESH]
  • |Sodium/*physiology[MESH]
  • |T-Lymphocytes/drug effects/*metabolism[MESH]


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