Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1111/j.1600-0412.2011.01082.x http://scihub22266oqcxt.onion/10.1111/j.1600-0412.2011.01082.x 21306340/?report=reader!5860914!21306340     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Acta+Obstet+Gynecol+Scand 2011 ; 90 (5): 510-5 Nephropedia Template TP {{tp|p=21306340|t=2011. Subtle perturbations of genital microflora alter mucosal immunity among low-risk pregnant women |pdf=|usr=}}{{21306340}} gab.com Text Subtle perturbations of genital microflora alter mucosal immunity among low-risk pregnant women JO: Acta Obstet Gynecol Scand http://www.kidney.de/pget.php?&tw=1&pmid=21306340 #FOAvip OBJECTIVE: Alteration in the vaginal flora has been associated with adverse pregnancy outcomes. The objective of this study was to examine the impact of changes in individual microflora on genital immunity among low-risk pregnant women in early pregnancy. DESIGN: Cross-sectional study. SETTING: Large, tertiary care, academic hospital clinic. POPULATION: Low-risk women were enrolled prior to 14 weeks' gestation. METHODS: Women were included if they had no medical or previous obstetrical complications, were non-smokers, had no sexually transmitted infections and no intercourse in the last 48 hours. Consenting women underwent speculum examination for collection of vaginal culture and Dacron swabs for cytokine analysis. Semi-quantitative vaginal cultures were performed in a reference laboratory. MAIN OUTCOME MEASURES: Concentrations of immune mediators were compared in the presence of various organisms. Concentrations were converted to multiples of the median to standardize the values of each mediator. Regression analyses were performed to control for race. RESULTS: We enrolled 47 women. The frequencies of genital microorganisms were: H(2)O(2) -producing lactobacilli (70%), Ureaplasma urealyticum (66%), Gardnerella vaginalis (45%), anaerobic non-pigmented Gram-negative rods (ANPGNR, 40%), anaerobic pigmented Gram-negative rods (APGNR, 17%). After adjusting for race and body mass index, interleukin-1beta, interferon-gamma, tumor necrosis factor-alpha and granulocyte macrophage-colony stimulating factor were increased in the presence of G. vaginalis, ANPGNR, and APGNR. There was no consistent impact on the other markers of immune activation. CONCLUSION: The presence of individual species impacts genital immunity among low-risk pregnant women. Perturbations in genital immunity could partially explain heterogeneity in adverse pregnancy outcomes. Twit Text FOAVip Subtle perturbations of genital microflora alter mucosal immunity among low-risk pregnant women ????Acta Obstet Gynecol Scand http://www.kidney.de/pget.php?&tw=1&pmid=21306340 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=21306340 #FOAvip English Wikipedia <ref>{{Cite pmid|21306340}}</ref> Subtle perturbations of genital microflora alter mucosal immunity among low-risk pregnant women #MMPMID21306340 Anderson BL; Cu-Uvin S; Raker CA; Fitzsimmons C; Hillier SL Acta Obstet Gynecol Scand 2011[May]; 90 (5): 510-5 PMID21306340show ga OBJECTIVE: Alteration in the vaginal flora has been associated with adverse pregnancy outcomes. The objective of this study was to examine the impact of changes in individual microflora on genital immunity among low-risk pregnant women in early pregnancy. DESIGN: Cross-sectional study. SETTING: Large, tertiary care, academic hospital clinic. POPULATION: Low-risk women were enrolled prior to 14 weeks' gestation. METHODS: Women were included if they had no medical or previous obstetrical complications, were non-smokers, had no sexually transmitted infections and no intercourse in the last 48 hours. Consenting women underwent speculum examination for collection of vaginal culture and Dacron swabs for cytokine analysis. Semi-quantitative vaginal cultures were performed in a reference laboratory. MAIN OUTCOME MEASURES: Concentrations of immune mediators were compared in the presence of various organisms. Concentrations were converted to multiples of the median to standardize the values of each mediator. Regression analyses were performed to control for race. RESULTS: We enrolled 47 women. The frequencies of genital microorganisms were: H(2)O(2) -producing lactobacilli (70%), Ureaplasma urealyticum (66%), Gardnerella vaginalis (45%), anaerobic non-pigmented Gram-negative rods (ANPGNR, 40%), anaerobic pigmented Gram-negative rods (APGNR, 17%). After adjusting for race and body mass index, interleukin-1beta, interferon-gamma, tumor necrosis factor-alpha and granulocyte macrophage-colony stimulating factor were increased in the presence of G. vaginalis, ANPGNR, and APGNR. There was no consistent impact on the other markers of immune activation. CONCLUSION: The presence of individual species impacts genital immunity among low-risk pregnant women. Perturbations in genital immunity could partially explain heterogeneity in adverse pregnancy outcomes. |Adult[MESH] |Biomarkers/*metabolism[MESH] |Cytokines/*metabolism[MESH] |Enterococcus[MESH] |Female[MESH] |Gardnerella vaginalis[MESH] |Gram-Negative Anaerobic Straight, Curved, and Helical Rods[MESH] |Granulocyte-Macrophage Colony-Stimulating Factor/metabolism[MESH] |Humans[MESH] |Interferon-gamma/metabolism[MESH] |Interleukin-1beta/metabolism[MESH] |Lactobacillus[MESH] |Mucous Membrane/*immunology/*microbiology[MESH] |Pregnancy[MESH] |Tumor Necrosis Factor-alpha/metabolism[MESH] |Ureaplasma urealyticum[MESH] |Vagina/*immunology/*microbiology[MESH]Subtle perturbations of genital microflora alter mucosal immunity amon(epmc).pdf DeepDyve Pubget Overpricing