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10.1007/978-94-007-0265-3_1

http://scihub22266oqcxt.onion/10.1007/978-94-007-0265-3_1
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21290287!4356010!21290287
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suck abstract from ncbi

pmid21290287      Adv+Exp+Med+Biol 2011 ; 704 (?): 1-23
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  • Structural biology of TRP channels #MMPMID21290287
  • Li M; Yu Y; Yang J
  • Adv Exp Med Biol 2011[]; 704 (?): 1-23 PMID21290287show ga
  • Structural studies on TRP channels, while limited, are poised for a quickened pace and rapid expansion. As of yet, no high-resolution structure of a full length TRP channel exists, but low-resolution electron cryomicroscopy structures have been obtained for 4 TRP channels, and high-resolution NMR and X-ray crystal structures have been obtained for the cytoplasmic domains, including an atypical protein kinase domain, ankyrin repeats, coiled coil domains and a Ca(2+)-binding domain, of 6 TRP channels. These structures enhance our understanding of TRP channel assembly and regulation. Continued technical advances in structural approaches promise a bright outlook for TRP channel structural biology.
  • |Crystallography, X-Ray[MESH]
  • |Microscopy, Electron[MESH]
  • |Models, Molecular[MESH]
  • |Nuclear Magnetic Resonance, Biomolecular[MESH]
  • |Protein Conformation[MESH]


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