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10.1016/j.ajog.2010.11.006 http://scihub22266oqcxt.onion/10.1016/j.ajog.2010.11.006 21272846!ä!21272846 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Am+J+Obstet+Gynecol 2011 ; 204 (4): 364.e1-8 Nephropedia Template TP {{tp|p=21272846|t=2011. Magnesium sulfate ameliorates maternal and fetal inflammation in a rat model of maternal infection |pdf=|usr=}}{{21272846}} gab.com Text Magnesium sulfate ameliorates maternal and fetal inflammation in a rat model of maternal infection JO: Am J Obstet Gynecol http://www.kidney.de/pget.php?&tw=1&pmid=21272846 #FOAvip OBJECTIVE: Magnesium sulfate is proposed to have neuroprotective effects in the offspring. We examined the effects of maternal magnesium sulfate administration on maternal and fetal inflammatory responses in a rat model of maternal infection. STUDY DESIGN: Pregnant rats were injected with saline, Gram-negative bacterial endotoxin lipopolysaccharide or lipopolysaccharide with magnesium sulfate (pre- and/or after lipopolysaccharide) to mimic infection. Maternal blood, amniotic fluid, fetal blood, and fetal brains were collected 4 hours after lipopolysaccharide and assayed for tumor necrosis factor, interleukin-6, monocyte chemoattractant protein-1, and growth-related oncogene-KC. In addition, the effect of magnesium sulfate on cytokine production by an astrocytoma cell line was assessed. RESULTS: Lipopolysaccharide administration induced tumor necrosis factor, interleukin-6, monocyte chemoattractant protein-1, and growth-related oncogene-KC expression in maternal and fetal compartments. Maternal magnesium sulfate treatment significantly attenuated lipopolysaccharide-induced multiple proinflammatory mediator levels in maternal and fetal compartments. CONCLUSION: Antenatal magnesium sulfate administration significantly ameliorated maternal, fetal, and gestational tissue-associated inflammatory responses in an experimental model of maternal infection. Twit Text FOAVip Magnesium sulfate ameliorates maternal and fetal inflammation in a rat model of maternal infection ????Am J Obstet Gynecol http://www.kidney.de/pget.php?&tw=1&pmid=21272846 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=21272846 #FOAvip English Wikipedia <ref>{{Cite pmid|21272846}}</ref> Magnesium sulfate ameliorates maternal and fetal inflammation in a rat model of maternal infection #MMPMID21272846 Tam Tam HB; Dowling O; Xue X; Lewis D; Rochelson B; Metz CN Am J Obstet Gynecol 2011[Apr]; 204 (4): 364.e1-8 PMID21272846show ga OBJECTIVE: Magnesium sulfate is proposed to have neuroprotective effects in the offspring. We examined the effects of maternal magnesium sulfate administration on maternal and fetal inflammatory responses in a rat model of maternal infection. STUDY DESIGN: Pregnant rats were injected with saline, Gram-negative bacterial endotoxin lipopolysaccharide or lipopolysaccharide with magnesium sulfate (pre- and/or after lipopolysaccharide) to mimic infection. Maternal blood, amniotic fluid, fetal blood, and fetal brains were collected 4 hours after lipopolysaccharide and assayed for tumor necrosis factor, interleukin-6, monocyte chemoattractant protein-1, and growth-related oncogene-KC. In addition, the effect of magnesium sulfate on cytokine production by an astrocytoma cell line was assessed. RESULTS: Lipopolysaccharide administration induced tumor necrosis factor, interleukin-6, monocyte chemoattractant protein-1, and growth-related oncogene-KC expression in maternal and fetal compartments. Maternal magnesium sulfate treatment significantly attenuated lipopolysaccharide-induced multiple proinflammatory mediator levels in maternal and fetal compartments. CONCLUSION: Antenatal magnesium sulfate administration significantly ameliorated maternal, fetal, and gestational tissue-associated inflammatory responses in an experimental model of maternal infection. |Amniotic Fluid/metabolism[MESH] |Animals[MESH] |Brain/metabolism[MESH] |Chemokine CCL2/genetics/metabolism[MESH] |Chemokine CXCL1/metabolism[MESH] |Disease Models, Animal[MESH] |Escherichia coli Infections/drug therapy[MESH] |Female[MESH] |Inflammation/*drug therapy/metabolism[MESH] |Interleukin-6/metabolism[MESH] |Interleukin-8/metabolism[MESH] |Magnesium Sulfate/*pharmacology[MESH] |Neuroprotective Agents/*pharmacology[MESH] |Pregnancy[MESH] |Pregnancy Complications, Infectious/*drug therapy[MESH] |RNA, Messenger/metabolism[MESH] |Rats[MESH] |Rats, Sprague-Dawley[MESH]Magnesium sulfate ameliorates maternal and fetal inflammation in a rat(epmc).pdf DeepDyve Pubget Overpricing