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10.1152/ajprenal.00742.2010

http://scihub22266oqcxt.onion/10.1152/ajprenal.00742.2010
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21270092!3074996!21270092
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suck abstract from ncbi

pmid21270092      Am+J+Physiol+Renal+Physiol 2011 ; 300 (4): F821-7
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  • Recent advances in distal tubular potassium handling #MMPMID21270092
  • Rodan AR; Cheng CJ; Huang CL
  • Am J Physiol Renal Physiol 2011[Apr]; 300 (4): F821-7 PMID21270092show ga
  • It is well known that sodium reabsorption and aldosterone play important roles in potassium secretion by the aldosterone-sensitive distal nephron. Sodium- and aldosterone-independent mechanisms also exist. This review focuses on some recent studies that provide novel insights into the sodium- and aldosterone-independent potassium secretion by the aldosterone-sensitive distal nephron. In addition, we discuss a study reporting on the regulation of the mammalian potassium kidney channel ROMK by intracellular and extracellular magnesium, which may be important in the pathogenesis of persistent hypokalemia in patients with concomitant potassium and magnesium deficiency. We also discuss outstanding questions and propose working models for future investigation.
  • |Aldosterone/*physiology[MESH]
  • |Humans[MESH]
  • |Kidney Tubules, Distal/*physiology[MESH]
  • |Potassium/*physiology[MESH]


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