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10.1242/dev.045500 http://scihub22266oqcxt.onion/10.1242/dev.045500 21138973!2998162!21138973     free     free     free       Development 2011 ; 138 (1): 9-22 Nephropedia Template TP {{tp|p=21138973|t=2011. Hippo signaling: growth control and beyond |pdf=|usr=}}{{21138973}} gab.com Text Hippo signaling: growth control and beyond JO: Development http://www.kidney.de/pget.php?&tw=1&pmid=21138973 #FOAvip The Hippo pathway has emerged as a conserved signaling pathway that is essential for the proper regulation of organ growth in Drosophila and vertebrates. Although the mechanisms of signal transduction of the core kinases Hippo/Mst and Warts/Lats are relatively well understood, less is known about the upstream inputs of the pathway and about the downstream cellular and developmental outputs. Here, we review recently discovered mechanisms that contribute to the dynamic regulation of Hippo signaling during Drosophila and vertebrate development. We also discuss the expanding diversity of Hippo signaling functions during development, discoveries that shed light on a complex regulatory system and provide exciting new insights into the elusive mechanisms that regulate organ growth and regeneration. Twit Text FOAVip Hippo signaling: growth control and beyond ????Development http://www.kidney.de/pget.php?&tw=1&pmid=21138973 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=21138973 #FOAvip English Wikipedia <ref>{{Cite pmid|21138973}}</ref> Hippo signaling: growth control and beyond #MMPMID21138973 Halder G; Johnson RL Development 2011[Jan]; 138 (1): 9-22 PMID21138973show ga The Hippo pathway has emerged as a conserved signaling pathway that is essential for the proper regulation of organ growth in Drosophila and vertebrates. Although the mechanisms of signal transduction of the core kinases Hippo/Mst and Warts/Lats are relatively well understood, less is known about the upstream inputs of the pathway and about the downstream cellular and developmental outputs. Here, we review recently discovered mechanisms that contribute to the dynamic regulation of Hippo signaling during Drosophila and vertebrate development. We also discuss the expanding diversity of Hippo signaling functions during development, discoveries that shed light on a complex regulatory system and provide exciting new insights into the elusive mechanisms that regulate organ growth and regeneration. |Animals[MESH] |Drosophila[MESH] |Drosophila Proteins/genetics/metabolism[MESH] |Gene Expression Regulation, Developmental/genetics/physiology[MESH] |Intracellular Signaling Peptides and Proteins/genetics/*metabolism[MESH] |Mice[MESH] |Models, Biological[MESH] |Organ Size/genetics/physiology[MESH] |Protein Serine-Threonine Kinases/genetics/metabolism[MESH]Hippo signaling: growth control and beyond (epmc).pdf DeepDyve Pubget Overpricing