Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1007/s13353-010-0005-1 http://scihub22266oqcxt.onion/10.1007/s13353-010-0005-1 21125367!3026673!21125367     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Appl+Genet 2011 ; 52 (1): 39-51 Nephropedia Template TP {{tp|p=21125367|t=2011. In vitro culturing of ciliary respiratory cells--a model for studies of genetic diseases |pdf=|usr=}}{{21125367}} gab.com Text In vitro culturing of ciliary respiratory cells--a model for studies of genetic diseases JO: J Appl Genet http://www.kidney.de/pget.php?&tw=1&pmid=21125367 #FOAvip Primary ciliary dyskinesia (PCD) is a rare genetic disorder caused by the impaired functioning of ciliated cells. Its diagnosis is based on the analysis of the structure and functioning of cilia present in the respiratory epithelium (RE) of the patient. Abnormalities of cilia caused by hereditary mutations closely resemble and often overlap with defects induced by the environmental factors. As a result, proper diagnosis of PCD is difficult and may require repeated sampling of patients' tissue, which is not always possible. The culturing of differentiated cells and tissues derived from the human RE seems to be the best way to diagnose PCD, to study genotype-phenotype relations of genes involved in ciliary dysfunction, as well as other aspects related to the functioning of the RE. In this review, different methods of culturing differentiated cells and tissues derived from the human RE, along with their potential and limitations, are summarized. Several considerations with respect to the factors influencing the process of in vitro differentiation (cell-to-cell interactions, medium composition, cell-support substrate) are also discussed. Twit Text FOAVip In vitro culturing of ciliary respiratory cells--a model for studies of genetic diseases ????J Appl Genet http://www.kidney.de/pget.php?&tw=1&pmid=21125367 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=21125367 #FOAvip English Wikipedia <ref>{{Cite pmid|21125367}}</ref> In vitro culturing of ciliary respiratory cells--a model for studies of genetic diseases #MMPMID21125367 Bukowy Z; Zietkiewicz E; Witt M J Appl Genet 2011[Feb]; 52 (1): 39-51 PMID21125367show ga Primary ciliary dyskinesia (PCD) is a rare genetic disorder caused by the impaired functioning of ciliated cells. Its diagnosis is based on the analysis of the structure and functioning of cilia present in the respiratory epithelium (RE) of the patient. Abnormalities of cilia caused by hereditary mutations closely resemble and often overlap with defects induced by the environmental factors. As a result, proper diagnosis of PCD is difficult and may require repeated sampling of patients' tissue, which is not always possible. The culturing of differentiated cells and tissues derived from the human RE seems to be the best way to diagnose PCD, to study genotype-phenotype relations of genes involved in ciliary dysfunction, as well as other aspects related to the functioning of the RE. In this review, different methods of culturing differentiated cells and tissues derived from the human RE, along with their potential and limitations, are summarized. Several considerations with respect to the factors influencing the process of in vitro differentiation (cell-to-cell interactions, medium composition, cell-support substrate) are also discussed. |*Genetic Diseases, Inborn[MESH] |Cells, Cultured[MESH] |Ciliary Motility Disorders/*genetics[MESH] |Humans[MESH]In vitro culturing of ciliary respiratory cells--a model for studies o(epmc).pdf DeepDyve Pubget Overpricing