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10.1159/000321791

http://scihub22266oqcxt.onion/10.1159/000321791
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21099215/?report=reader!3202928!21099215
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suck abstract from ncbi


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pmid21099215      Acta+Haematol 2011 ; 125 (3): 103-6
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  • Plasma glial fibrillary acidic protein levels in a child with sickle cell disease and stroke #MMPMID21099215
  • Savage WJ; Everett AD; Casella JF
  • Acta Haematol 2011[]; 125 (3): 103-6 PMID21099215show ga
  • A 12-year-old boy with HbSS sickle cell disease (SCD) was admitted with an acute febrile illness and developed overt stroke 3 days later. Plasma glial fibrillary acidic protein levels were elevated, as compared to pediatric controls, 32 h prior to the clinical diagnosis of stroke, peaked immediately prior to the exchange transfusion, and remained elevated 1 year later despite chronic transfusion therapy. Stroke in SCD can occur in the setting of acute illness, and a biomarker that could predict the onset and triage ill children to therapeutic intervention more quickly would be useful.
  • |*Predictive Value of Tests[MESH]
  • |Acute Disease[MESH]
  • |Anemia, Sickle Cell/blood/*complications[MESH]
  • |Biomarkers/blood[MESH]
  • |Child[MESH]
  • |Exchange Transfusion, Whole Blood[MESH]
  • |Glial Fibrillary Acidic Protein/*blood[MESH]
  • |Humans[MESH]
  • |Male[MESH]


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