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10.3109/17453674.2010.525201 http://scihub22266oqcxt.onion/10.3109/17453674.2010.525201 20919816/?report=reader!3216075!20919816     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Acta+Orthop 2010 ; 81 (6): 667-73 Nephropedia Template TP {{tp|p=20919816|t=2010. Incidence of low-grade infection in aseptic loosening of total hip arthroplasty |pdf=|usr=}}{{20919816}} gab.com Text Incidence of low-grade infection in aseptic loosening of total hip arthroplasty JO: Acta Orthop http://www.kidney.de/pget.php?&tw=1&pmid=20919816 #FOAvip PURPOSE: We investigated the hypothesis that many total hip arthroplasty revisions that are classified as aseptic are in fact low-grade infections missed with routine diagnostics. METHODS: In 7 Dutch hospitals, 176 consecutive patients with the preoperative diagnosis of aseptic loosening of their total hip arthroplasty were enrolled. During surgery, between 14 and 20 tissue samples were obtained for culture, pathology, and broad-range 16S rRNA PCR with reverse line blot hybridization. Patients were classified as either not being infected, suspected of having infection, or infected according to strict, predefined criteria. Each patient had a follow-up visit after 1 year. RESULTS: 7 patients were classified as infected, 4 of whom were not identified by routine culture. 15 additional patients were suspected of having infection. 20 of these 22 patients received a cemented prosthesis, fixated with antibiotic-loaded bone cement. All 22 patients received prophylactic systemic antibiotics. 7 of them reported complaints one year after surgery, but only one showed signs of early loosening. However, additional surgery was not performed in any of the patients. INTERPRETATION: Although the proportions were not as high as previously reported in the literature, between 4% and 13% of patients with the preoperative diagnosis of aseptic loosening were infected. However, as thorough debridement was performed during surgery and prophylactic antibiotics were used, the diagnosis of infection did not have any obvious clinical consequences, as most patients performed well at the 1-year follow-up. Whether this observation has implications for long-term implant survival remains to be seen. Twit Text FOAVip Incidence of low-grade infection in aseptic loosening of total hip arthroplasty ????Acta Orthop http://www.kidney.de/pget.php?&tw=1&pmid=20919816 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=20919816 #FOAvip English Wikipedia <ref>{{Cite pmid|20919816}}</ref> Incidence of low-grade infection in aseptic loosening of total hip arthroplasty #MMPMID20919816 Moojen DJ; van Hellemondt G; Vogely HC; Burger BJ; Walenkamp GH; Tulp NJ; Schreurs BW; de Meulemeester FR; Schot CS; van de Pol I; Fujishiro T; Schouls LM; Bauer TW; Dhert WJ Acta Orthop 2010[Dec]; 81 (6): 667-73 PMID20919816show ga PURPOSE: We investigated the hypothesis that many total hip arthroplasty revisions that are classified as aseptic are in fact low-grade infections missed with routine diagnostics. METHODS: In 7 Dutch hospitals, 176 consecutive patients with the preoperative diagnosis of aseptic loosening of their total hip arthroplasty were enrolled. During surgery, between 14 and 20 tissue samples were obtained for culture, pathology, and broad-range 16S rRNA PCR with reverse line blot hybridization. Patients were classified as either not being infected, suspected of having infection, or infected according to strict, predefined criteria. Each patient had a follow-up visit after 1 year. RESULTS: 7 patients were classified as infected, 4 of whom were not identified by routine culture. 15 additional patients were suspected of having infection. 20 of these 22 patients received a cemented prosthesis, fixated with antibiotic-loaded bone cement. All 22 patients received prophylactic systemic antibiotics. 7 of them reported complaints one year after surgery, but only one showed signs of early loosening. However, additional surgery was not performed in any of the patients. INTERPRETATION: Although the proportions were not as high as previously reported in the literature, between 4% and 13% of patients with the preoperative diagnosis of aseptic loosening were infected. However, as thorough debridement was performed during surgery and prophylactic antibiotics were used, the diagnosis of infection did not have any obvious clinical consequences, as most patients performed well at the 1-year follow-up. Whether this observation has implications for long-term implant survival remains to be seen. |Adult[MESH] |Aged[MESH] |Aged, 80 and over[MESH] |Arthroplasty, Replacement, Hip/*adverse effects[MESH] |Female[MESH] |Follow-Up Studies[MESH] |Hip Prosthesis/adverse effects[MESH] |Humans[MESH] |Incidence[MESH] |Male[MESH] |Middle Aged[MESH] |Netherlands/epidemiology[MESH] |Polymerase Chain Reaction[MESH] |Prospective Studies[MESH] |Prosthesis Failure[MESH] |Prosthesis-Related Infections/epidemiology/*etiology/microbiology[MESH]Incidence of low-grade infection in aseptic loosening of total hip art(epmc).pdf DeepDyve Pubget Overpricing