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10.5021/ad.2009.21.4.409

http://scihub22266oqcxt.onion/10.5021/ad.2009.21.4.409
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suck abstract from ncbi

pmid20523835      Ann+Dermatol 2009 ; 21 (4): 409-12
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  • Coexistence of amelanotic melanoma and liposarcoma #MMPMID20523835
  • Jeong TJ; Lee EJ; Haw S; Shin MK; Haw CR
  • Ann Dermatol 2009[Nov]; 21 (4): 409-12 PMID20523835show ga
  • An amelanotic malignant melanoma is characterized by little or no pigment. It is frequently misdiagnosed because it is a rare entity in general, and because of its unusual clinical features. Liposarcoma is one of the most common adult soft tissue sarcomas. We encountered a case of amelanotic melanoma with a concurrent liposarcoma. A 68-year-old man presented with a single, 1.5x1.5 cm round erythematous, eroded nodule on the left heel. A biopsy specimen showed atypical, pleomorphic tumor cells with little melanin pigment. The tumor cells were positive for S-100, HMB-45 and negative for cytokeratins. These findings were consistent with amelanotic melanoma. On positron emission tomography/computed tomography (PET/CT), a hypermetabolic lesion was found in the left buttock. This lesion was excised and diagnosed as a well-differentiated liposarcoma. An association between sarcomas and other primary malignancies has been reported. However, an association between melanoma and liposarcoma is rare.
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