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http://scihub22266oqcxt.onion/ 2047605!ä!2047605 Warning: Undefined variable $yww in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 538 Warning: Undefined variable $yww in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 538       Kokyu+To+Junkan 1991 ; 39 (3): 261-5 Nephropedia Template TP {{tp|p=2047605|t=1991. Efficacy of isoproterenol, magnesium sulfate and verapamil for torsade de pointes |pdf=|usr=}}{{2047605}} gab.com Text Efficacy of isoproterenol, magnesium sulfate and verapamil for torsade de pointes JO: Kokyu To Junkan http://www.kidney.de/pget.php?&tw=1&pmid=2047605 #FOAvip The efficacy of isoproterenol, MgSO4 and verapamil for torsade de pointes was evaluated in 60 dogs. Torsade de pointes was induced in 28 out of 60 dogs (46.7%) by ventricular stimulation after administration of quinidine sulfate (30 mg/kg). The electrophysiologic effect of isoproterenol (0.5 micrograms/min drip infusion) was studied in 9 dogs with torsade de pointes, in 9 dogs with MgSO4 (30 mg/kg), and in 10 dogs with verapamil (0.1 mg/kg bolus injection followed by 0.01 mg/kg/min drip infusion). If the first dose of these drugs was ineffective, ventricular stimulation was performed after the additional administration of the same dose. Isoproterenol significantly decreased QTc, ERP and dispersion of ERP but increased ERP/QT. MgSO4 significantly increased ERP and ERP/QT, however dispersion of ERP did not change. Verapamil induced no electrophysiologic changes in ventricular refractions . Isoproterenol prevented the occurrence of torsade de pointes in all dogs (100%), MgSO4 in 7 of 9 dogs (77.8%, 30 mg/kg in three and 60 mg/kg in four) and verapamil in 4 of 10 dogs (40%, 0.1 mg/kg in two and 0.2 mg/kg in two). These findings suggest that isoproterenol and MgSO4 increased ERP/QT, showing one of their antiarrhythmic effects. It also shows that isoproterenol and MgSO4 may be useful in the treatment of torsade de pointes. Twit Text FOAVip Efficacy of isoproterenol, magnesium sulfate and verapamil for torsade de pointes ????Kokyu To Junkan http://www.kidney.de/pget.php?&tw=1&pmid=2047605 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=2047605 #FOAvip English Wikipedia <ref>{{Cite pmid|2047605}}</ref> Efficacy of isoproterenol, magnesium sulfate and verapamil for torsade de pointes #MMPMID2047605 Yamamoto H; Bando S; Nishikado A; Hamai K; Yamamoto K; Shinohara A Kokyu To Junkan 1991[Mar]; 39 (3): 261-5 PMID2047605show ga The efficacy of isoproterenol, MgSO4 and verapamil for torsade de pointes was evaluated in 60 dogs. Torsade de pointes was induced in 28 out of 60 dogs (46.7%) by ventricular stimulation after administration of quinidine sulfate (30 mg/kg). The electrophysiologic effect of isoproterenol (0.5 micrograms/min drip infusion) was studied in 9 dogs with torsade de pointes, in 9 dogs with MgSO4 (30 mg/kg), and in 10 dogs with verapamil (0.1 mg/kg bolus injection followed by 0.01 mg/kg/min drip infusion). If the first dose of these drugs was ineffective, ventricular stimulation was performed after the additional administration of the same dose. Isoproterenol significantly decreased QTc, ERP and dispersion of ERP but increased ERP/QT. MgSO4 significantly increased ERP and ERP/QT, however dispersion of ERP did not change. Verapamil induced no electrophysiologic changes in ventricular refractions . Isoproterenol prevented the occurrence of torsade de pointes in all dogs (100%), MgSO4 in 7 of 9 dogs (77.8%, 30 mg/kg in three and 60 mg/kg in four) and verapamil in 4 of 10 dogs (40%, 0.1 mg/kg in two and 0.2 mg/kg in two). These findings suggest that isoproterenol and MgSO4 increased ERP/QT, showing one of their antiarrhythmic effects. It also shows that isoproterenol and MgSO4 may be useful in the treatment of torsade de pointes. |Animals[MESH] |Dogs[MESH] |Drug Evaluation, Preclinical[MESH] |Electrocardiography[MESH] |Isoproterenol/*therapeutic use[MESH] |Magnesium Sulfate/*therapeutic use[MESH] |Quinidine[MESH] |Torsades de Pointes/chemically induced/*drug therapy/physiopathology[MESH] Efficacy of isoproterenol, magnesium sulfate and verapamil for torsad(epmc).pdf DeepDyve Pubget Overpricing