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10.1007/s00705-010-0645-9 http://scihub22266oqcxt.onion/10.1007/s00705-010-0645-9 20333534!ä!20333534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Arch+Virol 2010 ; 155 (5): 789-93 Nephropedia Template TP {{tp|p=20333534|t=2010. Protein kinase C-dependent phosphorylation of Borna disease virus P protein is required for efficient viral spread |pdf=|usr=}}{{20333534}} gab.com Text Protein kinase C-dependent phosphorylation of Borna disease virus P protein is required for efficient viral spread JO: Arch Virol http://www.kidney.de/pget.php?&tw=1&pmid=20333534 #FOAvip Mutational analysis of the phosphate acceptor sites of the Borna disease virus (BDV) phosphoprotein (P) has suggested a role of phosphorylation for viral spread. However, the studied mutant viruses also had two amino acid exchanges in the X protein, because the reading frames of P and X overlap. To determine the relative contribution of P and X to viral attenuation, we studied a P variant with serine-to-leucine substitutions (P(S26L,S28L)) in which the wild-type X sequence was conserved. Viral spread of rBDV-P(S26L,S28L) was impaired in human oligodendroglioma cells and in adult rats. Thus, BDV-P phosphorylation contributes to efficient viral dissemination. Twit Text FOAVip Protein kinase C-dependent phosphorylation of Borna disease virus P protein is required for efficient viral spread ????Arch Virol http://www.kidney.de/pget.php?&tw=1&pmid=20333534 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=20333534 #FOAvip English Wikipedia <ref>{{Cite pmid|20333534}}</ref> Protein kinase C-dependent phosphorylation of Borna disease virus P protein is required for efficient viral spread #MMPMID20333534 Schmid S; Metz P; Prat CM; Gonzalez-Dunia D; Schwemmle M Arch Virol 2010[May]; 155 (5): 789-93 PMID20333534show ga Mutational analysis of the phosphate acceptor sites of the Borna disease virus (BDV) phosphoprotein (P) has suggested a role of phosphorylation for viral spread. However, the studied mutant viruses also had two amino acid exchanges in the X protein, because the reading frames of P and X overlap. To determine the relative contribution of P and X to viral attenuation, we studied a P variant with serine-to-leucine substitutions (P(S26L,S28L)) in which the wild-type X sequence was conserved. Viral spread of rBDV-P(S26L,S28L) was impaired in human oligodendroglioma cells and in adult rats. Thus, BDV-P phosphorylation contributes to efficient viral dissemination. |Animals[MESH] |Borna disease virus/*physiology[MESH] |Cells, Cultured[MESH] |Humans[MESH] |Phosphoproteins/*metabolism[MESH] |Phosphorylation[MESH] |Protein Kinase C/chemistry/*physiology[MESH] |Rats[MESH] |Rats, Inbred Lew[MESH]Protein kinase C-dependent phosphorylation of Borna disease virus P pr(epmc).pdf DeepDyve Pubget Overpricing