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10.1021/nn901889v http://scihub22266oqcxt.onion/10.1021/nn901889v 20148575/?report=reader!2858067!20148575     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       ACS+Nano 2010 ; 4 (3): 1305-12 Nephropedia Template TP {{tp|p=20148575|t=2010. Nano-optofluidic detection of single viruses and nanoparticles |pdf=|usr=}}{{20148575}} gab.com Text Nano-optofluidic detection of single viruses and nanoparticles JO: ACS Nano http://www.kidney.de/pget.php?&tw=1&pmid=20148575 #FOAvip The reliable detection, sizing, and sorting of viruses and nanoparticles is important for biosensing, environmental monitoring, and quality control. Here we introduce an optical detection scheme for the real-time and label-free detection and recognition of single viruses and larger proteins. The method makes use of nanofluidic channels in combination with optical interferometry. Elastically scattered light from single viruses traversing a stationary laser focus is detected with a differential heterodyne interferometer and the resulting signal allows single viruses to be characterized individually. Heterodyne detection eliminates phase variations due to different particle trajectories, thus improving the recognition accuracy as compared to standard optical interferometry. We demonstrate the practicality of our approach by resolving nanoparticles of various sizes, and detecting and recognizing different species of human viruses from a mixture. The detection system can be readily integrated into larger nanofluidic architectures for practical applications. Twit Text FOAVip Nano-optofluidic detection of single viruses and nanoparticles ????ACS Nano http://www.kidney.de/pget.php?&tw=1&pmid=20148575 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=20148575 #FOAvip English Wikipedia <ref>{{Cite pmid|20148575}}</ref> Nano-optofluidic detection of single viruses and nanoparticles #MMPMID20148575 Mitra A; Deutsch B; Ignatovich F; Dykes C; Novotny L ACS Nano 2010[Mar]; 4 (3): 1305-12 PMID20148575show ga The reliable detection, sizing, and sorting of viruses and nanoparticles is important for biosensing, environmental monitoring, and quality control. Here we introduce an optical detection scheme for the real-time and label-free detection and recognition of single viruses and larger proteins. The method makes use of nanofluidic channels in combination with optical interferometry. Elastically scattered light from single viruses traversing a stationary laser focus is detected with a differential heterodyne interferometer and the resulting signal allows single viruses to be characterized individually. Heterodyne detection eliminates phase variations due to different particle trajectories, thus improving the recognition accuracy as compared to standard optical interferometry. We demonstrate the practicality of our approach by resolving nanoparticles of various sizes, and detecting and recognizing different species of human viruses from a mixture. The detection system can be readily integrated into larger nanofluidic architectures for practical applications. |*Optical Phenomena[MESH] |Humans[MESH] |Nanoparticles/*analysis/chemistry[MESH] |Nanotechnology/*instrumentation[MESH] |Particle Size[MESH] |Signal Processing, Computer-Assisted[MESH] |Time Factors[MESH]Nano-optofluidic detection of single viruses and nanoparticles (epmc).pdf DeepDyve Pubget Overpricing