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10.1016/j.conb.2009.12.002 http://scihub22266oqcxt.onion/10.1016/j.conb.2009.12.002 20080044!2829308!20080044     free     free     free       Curr+Opin+Neurobiol 2010 ; 20 (1): 58-67 Nephropedia Template TP {{tp|p=20080044|t=2010. Role of primary cilia in brain development and cancer |pdf=|usr=}}{{20080044}} gab.com Text Role of primary cilia in brain development and cancer JO: Curr Opin Neurobiol http://www.kidney.de/pget.php?&tw=1&pmid=20080044 #FOAvip The primary cilium, a hair-like extension from a cell's surface, acts as a sensory organelle to receive signals that regulate cellular behavior and physiology. Like most mammalian cells, neural progenitors and neurons have primary cilia. Recent studies show that this tiny projection plays important roles in brain development and diseases. Ciliary mutant mice show defects in brain patterning, progenitor proliferation, and specification of adult neural stem cells. Primary cilia also have dual opposing functions in the development of brain tumors. Ciliary defects are associated with genetic syndromes that frequently have neurological symptoms. Understanding the multifaceted roles that primary cilia have in brain development will provide important insights into the mechanism of brain development and diseases. Twit Text FOAVip Role of primary cilia in brain development and cancer ????Curr Opin Neurobiol http://www.kidney.de/pget.php?&tw=1&pmid=20080044 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=20080044 #FOAvip English Wikipedia <ref>{{Cite pmid|20080044}}</ref> Role of primary cilia in brain development and cancer #MMPMID20080044 Han YG; Alvarez-Buylla A Curr Opin Neurobiol 2010[Feb]; 20 (1): 58-67 PMID20080044show ga The primary cilium, a hair-like extension from a cell's surface, acts as a sensory organelle to receive signals that regulate cellular behavior and physiology. Like most mammalian cells, neural progenitors and neurons have primary cilia. Recent studies show that this tiny projection plays important roles in brain development and diseases. Ciliary mutant mice show defects in brain patterning, progenitor proliferation, and specification of adult neural stem cells. Primary cilia also have dual opposing functions in the development of brain tumors. Ciliary defects are associated with genetic syndromes that frequently have neurological symptoms. Understanding the multifaceted roles that primary cilia have in brain development will provide important insights into the mechanism of brain development and diseases. |Animals[MESH] |Body Patterning/physiology[MESH] |Brain/*growth & development[MESH] |Cerebellar Neoplasms/*etiology[MESH] |Cilia/physiology[MESH] |Humans[MESH] |Medulloblastoma/*etiology[MESH]Role of primary cilia in brain development and cancer (epmc).pdf DeepDyve Pubget Overpricing