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10.1111/j.1365-2796.1991.tb00330.x

http://scihub22266oqcxt.onion/10.1111/j.1365-2796.1991.tb00330.x
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1997644!ä!1997644

suck abstract from ncbi


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pmid1997644      J+Intern+Med 1991 ; 229 (2): 193-6
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  • Gastric lymphoma causing granulocytopenia and cold intolerance, with recovery after treatment #MMPMID1997644
  • Stavem P; Rorvik T; Brandtzaeg P; Brosstad F; Nordhagen R; Grabner P
  • J Intern Med 1991[Feb]; 229 (2): 193-6 PMID1997644show ga
  • A 34-year-old man was found to have granulocytopenia with a white blood count of 2.3 x 10(9) l-1, consisting of 10% segmented neutrophils, 50% monocytes and 40% lymphocytes. A bone marrow aspirate showed 20% promyelocytes and 10% blasts with monoblastic features, and a smouldering myelomonocytic leukaemia was considered to be a possible diagnosis. In cold weather the patient experienced cold intolerance with acrocyanosis and small ulcerations on the ears. The test for heparin-precipitable protein ('cryofibrinogen') was strongly positive. During the following year, these signs and symptoms persisted, and the patient also developed constant moderate pain in the epigastric region. Gastroscopy revealed a large lymphoma of the stomach, which was a high-grade malignant centroblastic type of non-Hodgkin's lymphoma. After successful removal of the tumour, and six courses of potent cytostatic combinations, the patient recovered completely, and the granulocytopenia and cold intolerance disappeared.
  • |Adult[MESH]
  • |Agranulocytosis/*etiology[MESH]
  • |Combined Modality Therapy[MESH]
  • |Humans[MESH]
  • |Lymphoma, Non-Hodgkin/*complications/therapy[MESH]
  • |Male[MESH]
  • |Raynaud Disease/*etiology[MESH]
  • |Remission Induction[MESH]


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