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10.1016/j.ajem.2008.11.014

http://scihub22266oqcxt.onion/10.1016/j.ajem.2008.11.014
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19857426!ä!19857426

suck abstract from ncbi


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pmid19857426      Am+J+Emerg+Med 2009 ; 27 (8): 1016.e1-3
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  • Long QT syndrome and torsades de pointes induced by acute sulpiride poisoning #MMPMID19857426
  • Chang JH; Weng TI; Fang CC
  • Am J Emerg Med 2009[Oct]; 27 (8): 1016.e1-3 PMID19857426show ga
  • Sulpiride, a selective dopamine D2 antagonist and a substituted benzamide derivative, is considered a safe antipsychotic and antidepressant agent with few adverse effects on the cardiovascular system. Sulpiride-induced torsades de pointes is rare. We report a case of long QT syndrome and torsades de pointes induced by ingestion of 1.5 g of sulpiride. Ventricular arrhythmia was initially treated with amiodarone, without success. Eventually, lidocaine and magnesium sulfate successfully terminated the ventricular arrhythmia. The patient was discharged uneventfully after 3 days of hospitalization. This case illustrates the fact that acute sulpiride poisoning may lead to life-threatening ventricular arrhythmia. Early recognition followed by effective therapy is crucial. Intensive cardiac monitoring is recommended for sulpiride poisoning.
  • |Dopamine Antagonists/*poisoning[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Lidocaine/therapeutic use[MESH]
  • |Long QT Syndrome/*chemically induced[MESH]
  • |Magnesium Sulfate/therapeutic use[MESH]
  • |Sulpiride/*poisoning[MESH]
  • |Torsades de Pointes/*chemically induced[MESH]


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