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10.1002/jmv.21638 http://scihub22266oqcxt.onion/10.1002/jmv.21638 19856479!ä!19856479 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Med+Virol 2009 ; 81 (12): 2079-88 Nephropedia Template TP {{tp|p=19856479|t=2009. Intrahepatic long-term persistence of parvovirus B19 and its role in chronic viral hepatitis |pdf=|usr=}}{{19856479}} gab.com Text Intrahepatic long-term persistence of parvovirus B19 and its role in chronic viral hepatitis JO: J Med Virol http://www.kidney.de/pget.php?&tw=1&pmid=19856479 #FOAvip Parvovirus B19 (B19V) has been detected in the liver of Asian patients infected with HBV and may contribute to acute and chronic liver disease. This study aimed to investigate the impact of B19V infection in European patients with viral hepatitis. B19V DNA was detected in 1/91 and 0/50 serum samples from patients with chronic hepatitis C and B, respectively. In contrast, B19V DNA was amplified frequently from explanted end-stage liver tissues (37/50, 74%) and from routine biopsy samples (14/32, 44%) (P < 0.05). However, there was no significant difference in B19V copy number per cell between these two groups. B19V-specific CD4(+) T-cell responses to two dominant MHC-class-restricted epitopes were detected in a similar frequency in healthy anti-B19V-positive individuals (3/19; 16%) and patients with chronic hepatitis C (3/13; 23%). These results indicate that B19V can persist in the liver. However, there is no evidence that B19V is a "hepatitis virus" worsening liver disease in European patients with chronic hepatitis C. Twit Text FOAVip Intrahepatic long-term persistence of parvovirus B19 and its role in chronic viral hepatitis ????J Med Virol http://www.kidney.de/pget.php?&tw=1&pmid=19856479 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=19856479 #FOAvip English Wikipedia <ref>{{Cite pmid|19856479}}</ref> Intrahepatic long-term persistence of parvovirus B19 and its role in chronic viral hepatitis #MMPMID19856479 Wang C; Heim A; Schlaphoff V; Suneetha PV; Stegmann KA; Jiang H; Krueger M; Fytili P; Schulz T; Cornberg M; Kandolf R; Manns MP; Bock CT; Wedemeyer H J Med Virol 2009[Dec]; 81 (12): 2079-88 PMID19856479show ga Parvovirus B19 (B19V) has been detected in the liver of Asian patients infected with HBV and may contribute to acute and chronic liver disease. This study aimed to investigate the impact of B19V infection in European patients with viral hepatitis. B19V DNA was detected in 1/91 and 0/50 serum samples from patients with chronic hepatitis C and B, respectively. In contrast, B19V DNA was amplified frequently from explanted end-stage liver tissues (37/50, 74%) and from routine biopsy samples (14/32, 44%) (P < 0.05). However, there was no significant difference in B19V copy number per cell between these two groups. B19V-specific CD4(+) T-cell responses to two dominant MHC-class-restricted epitopes were detected in a similar frequency in healthy anti-B19V-positive individuals (3/19; 16%) and patients with chronic hepatitis C (3/13; 23%). These results indicate that B19V can persist in the liver. However, there is no evidence that B19V is a "hepatitis virus" worsening liver disease in European patients with chronic hepatitis C. |Adult[MESH] |Aged[MESH] |Antibodies, Viral/immunology[MESH] |CD4-Positive T-Lymphocytes/immunology[MESH] |DNA, Viral/genetics/isolation & purification[MESH] |Disease Progression[MESH] |Female[MESH] |Germany[MESH] |Hepatitis B, Chronic/complications/immunology/pathology/*virology[MESH] |Hepatitis C, Chronic/complications/immunology/pathology/*virology[MESH] |Humans[MESH] |Liver/pathology/*virology[MESH] |Male[MESH] |Middle Aged[MESH] |Parvoviridae Infections/complications/immunology/*virology[MESH] |Parvovirus B19, Human/genetics/immunology/*isolation & purification[MESH]Intrahepatic long-term persistence of parvovirus B19 and its role in c(epmc).pdf DeepDyve Pubget Overpricing