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10.1152/japplphysiol.00393.2009 http://scihub22266oqcxt.onion/10.1152/japplphysiol.00393.2009 19745194!ä!19745194 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Appl+Physiol+(1985) 2009 ; 107 (5): 1472-8 Nephropedia Template TP {{tp|p=19745194|t=2009. Protective mechanical ventilation does not exacerbate lung function impairment or lung inflammation following influenza A infection |pdf=|usr=}}{{19745194}} gab.com Text Protective mechanical ventilation does not exacerbate lung function impairment or lung inflammation following influenza A infection JO: J Appl Physiol (1985) http://www.kidney.de/pget.php?&tw=1&pmid=19745194 #FOAvip The degree to which mechanical ventilation induces ventilator-associated lung injury is dependent on the initial acute lung injury (ALI). Viral-induced ALI is poorly studied, and this study aimed to determine whether ALI induced by a clinically relevant infection is exacerbated by protective mechanical ventilation. Adult female BALB/c mice were inoculated with 10(4.5) plaque-forming units of influenza A/Mem/1/71 in 50 microl of medium or medium alone. This study used a protective ventilation strategy, whereby mice were anesthetized, tracheostomized, and mechanically ventilated for 2 h. Lung mechanics were measured periodically throughout the ventilation period using a modification of the forced oscillation technique to obtain measures of airway resistance and coefficients of tissue damping and tissue elastance. Thoracic gas volume was measured and used to obtain specific airway resistance, tissue damping, and tissue elastance. At the end of the ventilation period, a bronchoalveolar lavage sample was collected to measure inflammatory cells, macrophage inflammatory protein-2, IL-6, TNF-alpha, and protein leak. Influenza infection caused significant increases in inflammatory cells, protein leak, and deterioration in lung mechanics that were not exacerbated by mechanical ventilation, in contrast to previous studies using bacterial and mouse-specific viral infection. This study highlighted the importance of type and severity of lung injury in determining outcome following mechanical ventilation. Twit Text FOAVip Protective mechanical ventilation does not exacerbate lung function impairment or lung inflammation following influenza A infection ????J Appl Physiol (1985) http://www.kidney.de/pget.php?&tw=1&pmid=19745194 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=19745194 #FOAvip English Wikipedia <ref>{{Cite pmid|19745194}}</ref> Protective mechanical ventilation does not exacerbate lung function impairment or lung inflammation following influenza A infection #MMPMID19745194 Zosky GR; Cannizzaro V; Hantos Z; Sly PD J Appl Physiol (1985) 2009[Nov]; 107 (5): 1472-8 PMID19745194show ga The degree to which mechanical ventilation induces ventilator-associated lung injury is dependent on the initial acute lung injury (ALI). Viral-induced ALI is poorly studied, and this study aimed to determine whether ALI induced by a clinically relevant infection is exacerbated by protective mechanical ventilation. Adult female BALB/c mice were inoculated with 10(4.5) plaque-forming units of influenza A/Mem/1/71 in 50 microl of medium or medium alone. This study used a protective ventilation strategy, whereby mice were anesthetized, tracheostomized, and mechanically ventilated for 2 h. Lung mechanics were measured periodically throughout the ventilation period using a modification of the forced oscillation technique to obtain measures of airway resistance and coefficients of tissue damping and tissue elastance. Thoracic gas volume was measured and used to obtain specific airway resistance, tissue damping, and tissue elastance. At the end of the ventilation period, a bronchoalveolar lavage sample was collected to measure inflammatory cells, macrophage inflammatory protein-2, IL-6, TNF-alpha, and protein leak. Influenza infection caused significant increases in inflammatory cells, protein leak, and deterioration in lung mechanics that were not exacerbated by mechanical ventilation, in contrast to previous studies using bacterial and mouse-specific viral infection. This study highlighted the importance of type and severity of lung injury in determining outcome following mechanical ventilation. |*Respiratory Mechanics[MESH] |Acute Lung Injury/etiology/*physiopathology/*prevention & control[MESH] |Animals[MESH] |Cytokines/metabolism[MESH] |Disease Models, Animal[MESH] |Female[MESH] |Humans[MESH] |Influenza, Human/complications/*physiopathology/*rehabilitation[MESH] |Mice[MESH] |Mice, Inbred C57BL[MESH] |Respiration, Artificial/*adverse effects[MESH] |Treatment Outcome[MESH]Protective mechanical ventilation does not exacerbate lung function im(epmc).pdf DeepDyve Pubget Overpricing