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10.1016/j.gde.2009.04.008 http://scihub22266oqcxt.onion/10.1016/j.gde.2009.04.008 19477114!2953615!19477114     free     free     free  :  Publisher Nephropedia Template TP {{tp|p=19477114|t=2009. The primary cilium as a cellular signaling center: lessons from disease |pdf=|usr=}} gab.com Text The primary cilium as a cellular signaling center: lessons from disease JO: Curr Opin Genet Dev http://www.kidney.de/pget.php?&tw=1&pmid=19477114 #FOAvip Genetic diseases known as ciliopathies have recently entered the limelight, placing new importance on a previously mysterious organelle: the primary cilium. Mutations affecting the primary cilium in both humans and animal models can lead to a plethora of distinct phenotypes including retinal degeneration, kidney cysts, and brain malformations. New findings are quickly lending insight into the functions of this cellular extension that seems to be especially important in modulation of subcellular signaling cascades at various stages of development and adult homeostasis. Twit Text FOAVip The primary cilium as a cellular signaling center: lessons from disease 🦆🦆Curr Opin Genet Dev http://www.kidney.de/pget.php?&tw=1&pmid=19477114 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=19477114 #FOAvip English Wikipedia <ref>{{Cite pmid|19477114}}</ref> The primary cilium as a cellular signaling center: lessons from disease #MMPMID19477114 Lancaster MA; Gleeson JG Curr Opin Genet Dev 2009[Jun]; 19 (3): 220-9 PMID19477114show ga Genetic diseases known as ciliopathies have recently entered the limelight, placing new importance on a previously mysterious organelle: the primary cilium. Mutations affecting the primary cilium in both humans and animal models can lead to a plethora of distinct phenotypes including retinal degeneration, kidney cysts, and brain malformations. New findings are quickly lending insight into the functions of this cellular extension that seems to be especially important in modulation of subcellular signaling cascades at various stages of development and adult homeostasis. |*Signal Transduction[MESH] |Animals[MESH] |Bardet-Biedl Syndrome/genetics/metabolism/pathology[MESH] |Biological Transport[MESH] |Cilia/genetics/metabolism/*pathology[MESH] |Genetic Predisposition to Disease[MESH] |Humans[MESH] |Kartagener Syndrome/genetics/metabolism/pathology[MESH] |Models, Biological[MESH] |Polycystic Kidney Diseases/genetics/metabolism/pathology[MESH]The primary cilium as a cellular signaling center: lessons from diseas(epmc).pdf DeepDyve Pubget Overpricing