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10.2174/138920207783591681

http://scihub22266oqcxt.onion/10.2174/138920207783591681
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19412419!2647155!19412419
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suck abstract from ncbi

pmid19412419      Curr+Genomics 2007 ; 8 (7): 476-83
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  • Incomplete coverage of candidate genes: a poorly considered bias #MMPMID19412419
  • Drago A; De Ronchi D; Serretti A
  • Curr Genomics 2007[Nov]; 8 (7): 476-83 PMID19412419show ga
  • Current genetic investigations are performed both on the basis of a rational and biologically based choice of candidate genes and through genome wide scans. Nonetheless, lack of replication is a common problem in psychiatric genetics as well as in other genetic fields. There are a number of reasons for this inconsistency, among them a well known but poorly considered issue is gene coverage. The aim of the present paper is to focus on this well known and defectively deemed bias, especially when a candidate gene approach is chosen. The rational and the technical feasibility of this proposal are discussed as well as a survey of current investigations. The known consistent methodology to fix this bias is also discussed.
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