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19261976!ä!19261976

suck abstract from ncbi


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pmid19261976      J+Physiol+Pharmacol 2008 ; 59 Suppl 9 (ä): 121-35
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  • Purinergic regulation of glomerular microvasculature and tubular function #MMPMID19261976
  • Jankowski M
  • J Physiol Pharmacol 2008[Dec]; 59 Suppl 9 (ä): 121-35 PMID19261976show ga
  • Purinergic molecules: ATP, ADP and adenosine regulate physiological processes through activation of purinoceptors in the plasma membrane. Experimental evidence supports the view that purinergic molecules affect glomerular and tubular functions. Purinergic molecule-induced changes of tension of mesangial cells and/or podocytes may influence GFR by affecting the glomerular ultrafiltration coefficient. On the other hand, purinoceptors are crucial for electrolyte and fluid homeostasis by modulating activity of sodium-potassium-ATPase, voltage-independent or -dependent ion channels and cAMP-dependent water channels.
  • |Adenosine Diphosphate/*metabolism[MESH]
  • |Adenosine Triphosphate/*metabolism[MESH]
  • |Adenosine/*metabolism[MESH]
  • |Animals[MESH]
  • |Electrolytes/metabolism[MESH]
  • |Glomerular Filtration Rate/physiology[MESH]
  • |Homeostasis[MESH]
  • |Humans[MESH]
  • |Kidney Glomerulus/blood supply/*metabolism[MESH]
  • |Kidney Tubules/metabolism[MESH]
  • |Microcirculation[MESH]


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