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10.1099/vir.0.2008/001180-0

http://scihub22266oqcxt.onion/10.1099/vir.0.2008/001180-0
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18753240!ä!18753240

suck abstract from ncbi


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pmid18753240      J+Gen+Virol 2008 ; 89 (Pt 9): 2299-2302
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  • A third genotype of the human parvovirus PARV4 in sub-Saharan Africa #MMPMID18753240
  • Simmonds P; Douglas J; Bestetti G; Longhi E; Antinori S; Parravicini C; Corbellino M
  • J Gen Virol 2008[Sep]; 89 (Pt 9): 2299-2302 PMID18753240show ga
  • PARV4 is a recently discovered human parvovirus widely distributed in injecting drug users in the USA and Europe, particularly in those co-infected with human immunodeficiency virus (HIV). Like parvovirus B19, PARV4 persists in previously exposed individuals. In bone marrow and lymphoid tissue, PARV4 sequences were detected in two sub-Saharan African study subjects with AIDS but without a reported history of parenteral exposure and who were uninfected with hepatitis C virus. PARV4 variants infecting these subjects were phylogenetically distinct from genotypes 1 and 2 (formerly PARV5) that were reported previously. Analysis of near-complete genome sequences demonstrated that they should be classified as a third (equidistant) PARV4 genotype. The availability of a further near-complete genome sequence of this novel genotype facilitated identification of conserved novel open reading frames embedded in the ORF2 coding sequence; one encoded a putative protein with identifiable homology to SAT proteins of members of the genus Parvovirus.
  • |Acquired Immunodeficiency Syndrome/complications[MESH]
  • |Africa South of the Sahara[MESH]
  • |Amino Acid Sequence[MESH]
  • |Genotype[MESH]
  • |Humans[MESH]
  • |Molecular Sequence Data[MESH]
  • |Open Reading Frames[MESH]
  • |Parvoviridae Infections/complications/virology[MESH]
  • |Parvovirus/*classification/*genetics/isolation & purification[MESH]
  • |Phylogeny[MESH]


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