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10.1111/j.1600-0560.2007.00974.x http://scihub22266oqcxt.onion/10.1111/j.1600-0560.2007.00974.x 18537856!ä!18537856 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Cutan+Pathol 2008 ; 35 Suppl 1 (ä): 20-5 Nephropedia Template TP {{tp|p=18537856|t=2008. Parvovirus B19-associated catastrophic endothelialitis with a Degos-like presentation |pdf=|usr=}}{{18537856}} gab.com Text Parvovirus B19-associated catastrophic endothelialitis with a Degos-like presentation JO: J Cutan Pathol http://www.kidney.de/pget.php?&tw=1&pmid=18537856 #FOAvip Parvovirus B19 is a single-stranded DNA virus exhibiting affinity for a variety of cell types including endothelial cells. The basis of the affinity is globoside expression, the receptor for B19. B19 endothelial cell parasitism accelerates endothelial cell apoptosis, potentially critical in inducing neoantigenicity and secondary antibody formation. A 38-year-old previously healthy male developed intestinal and cutaneous infarction, elevated creatinine phosphokinase (CPK) levels and progressive cytopenias. The basis of his clinical presentation was unclear until a skin biopsy suggested a potential role for virally mediated endothelial cell injury. Hematoxylin and eosin, immunohistochemical, immunofluorescent and reverse transcriptase in situ polymerase chain reaction studies were conducted on skin biopsies to assess for viral triggers. B19 viremia and localization of B19 RNA transcripts to vascular endothelium were uncovered. A diagnosis of catastrophic endothelial cell injury attributable to B19 infection was rendered. The patient showed significant improvement with intravenous immunoglobulin (IVIG). Parvovirus B19 is a ubiquitous virus that in the majority of affected patients remains asymptomatic. Nevertheless, because of its ability to infect endothelium it can cause severe multiorgan endothelial cell injury. Twit Text FOAVip Parvovirus B19-associated catastrophic endothelialitis with a Degos-like presentation ????J Cutan Pathol http://www.kidney.de/pget.php?&tw=1&pmid=18537856 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=18537856 #FOAvip English Wikipedia <ref>{{Cite pmid|18537856}}</ref> Parvovirus B19-associated catastrophic endothelialitis with a Degos-like presentation #MMPMID18537856 Dyrsen ME; Iwenofu OH; Nuovo G; Magro CM J Cutan Pathol 2008[Oct]; 35 Suppl 1 (ä): 20-5 PMID18537856show ga Parvovirus B19 is a single-stranded DNA virus exhibiting affinity for a variety of cell types including endothelial cells. The basis of the affinity is globoside expression, the receptor for B19. B19 endothelial cell parasitism accelerates endothelial cell apoptosis, potentially critical in inducing neoantigenicity and secondary antibody formation. A 38-year-old previously healthy male developed intestinal and cutaneous infarction, elevated creatinine phosphokinase (CPK) levels and progressive cytopenias. The basis of his clinical presentation was unclear until a skin biopsy suggested a potential role for virally mediated endothelial cell injury. Hematoxylin and eosin, immunohistochemical, immunofluorescent and reverse transcriptase in situ polymerase chain reaction studies were conducted on skin biopsies to assess for viral triggers. B19 viremia and localization of B19 RNA transcripts to vascular endothelium were uncovered. A diagnosis of catastrophic endothelial cell injury attributable to B19 infection was rendered. The patient showed significant improvement with intravenous immunoglobulin (IVIG). Parvovirus B19 is a ubiquitous virus that in the majority of affected patients remains asymptomatic. Nevertheless, because of its ability to infect endothelium it can cause severe multiorgan endothelial cell injury. |Adult[MESH] |DNA, Viral[MESH] |Endothelial Cells/*pathology/*virology[MESH] |Fluorescent Antibody Technique[MESH] |Humans[MESH] |Immunoglobulins, Intravenous/therapeutic use[MESH] |Immunohistochemistry[MESH] |Intestines/blood supply/pathology/virology[MESH] |Ischemia/virology[MESH] |Male[MESH] |Malignant Atrophic Papulosis/*pathology[MESH] |Muscle Weakness/virology[MESH] |Parvoviridae Infections/drug therapy/*pathology/*physiopathology[MESH] |Reverse Transcriptase Polymerase Chain Reaction[MESH] |Skin/blood supply/pathology/virology[MESH]Parvovirus B19-associated catastrophic endothelialitis with a Degos-li(epmc).pdf DeepDyve Pubget Overpricing