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10.1007/s00011-007-7077-3

http://scihub22266oqcxt.onion/10.1007/s00011-007-7077-3
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18516713!ä!18516713

suck abstract from ncbi


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pmid18516713      Inflamm+Res 2008 ; 57 (6): 279-86
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  • Effects of magnesium supplementation on the glutathione redox system in atopic asthmatic children #MMPMID18516713
  • Bede O; Nagy D; Suranyi A; Horvath I; Szlavik M; Gyurkovits K
  • Inflamm Res 2008[Jun]; 57 (6): 279-86 PMID18516713show ga
  • OBJECTIVE: Our aim was to investigate the effects of 12-week oral magnesium (Mg) supplementation on the RBC redox system in stable, persistent, moderately asthmatic children (N = 40, 24 boys, 16 girls) aged 4-16 years in a randomized, double-blind, placebo-controlled study. DESIGN: Oxidized (GSSG) and reduced (GSH) glutathione, oxyhaemoglobin, methaemoglobin (metHb), hemichrome and bilirubin levels before and after treatment were determined, and GSH stability tests were performed. RESULT: The GSH concentration was significantly higher in the Mg-treated than in the placebo-treated patients after the treatment period. There was a positive correlation between the decreased plasma metHb and hemichrome levels and the decreased plasma haemoglobin concentrations in the Mg-treated patients at the end of the study. CONCLUSION: Mg in the given doses exerts antioxidant activity and influences the glutathione redox system.
  • |*Dietary Supplements[MESH]
  • |Adolescent[MESH]
  • |Asthma/*diet therapy/*drug therapy/immunology[MESH]
  • |Child[MESH]
  • |Child, Preschool[MESH]
  • |Double-Blind Method[MESH]
  • |Female[MESH]
  • |Forced Expiratory Volume[MESH]
  • |Glutathione/chemistry/*metabolism[MESH]
  • |Hemeproteins/metabolism[MESH]
  • |Hemoglobins/chemistry/metabolism[MESH]
  • |Humans[MESH]
  • |Magnesium/*therapeutic use[MESH]
  • |Male[MESH]
  • |Oxidation-Reduction[MESH]
  • |Oxidative Stress[MESH]


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