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10.2174/138955708784223530

http://scihub22266oqcxt.onion/10.2174/138955708784223530
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18473937!ä!18473937

suck abstract from ncbi

pmid18473937      Mini+Rev+Med+Chem 2008 ; 8 (5): 491-5
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  • Future target molecules for influenza treatment #MMPMID18473937
  • Uchide N; Toyoda H
  • Mini Rev Med Chem 2008[May]; 8 (5): 491-5 PMID18473937show ga
  • Induction of apoptosis and pro-inflammatory cytokine gene expression in influenza virus-infected cells activates production of toxic superoxide by macrophages. Pyrrolidine dithiocarbamate and nordihydroguaiaretic acid inhibit influenza virus proliferation and scavenge superoxide. These results suggest that they can be potential candidates for a drug of choice for influenza chemotherapy.
  • |Apoptosis/drug effects[MESH]
  • |Cell Proliferation/drug effects[MESH]
  • |Cytokines/drug effects/genetics/immunology[MESH]
  • |Gene Expression/drug effects[MESH]
  • |Humans[MESH]
  • |Influenza, Human/*drug therapy/genetics/metabolism[MESH]
  • |Masoprocol/chemistry/pharmacology/*therapeutic use[MESH]
  • |Pyrrolidines/chemistry/pharmacology/*therapeutic use[MESH]
  • |Superoxides/antagonists & inhibitors[MESH]


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