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10.1002/jmv.21187 http://scihub22266oqcxt.onion/10.1002/jmv.21187 18461615!ä!18461615 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Med+Virol 2008 ; 80 (7): 1243-51 Nephropedia Template TP {{tp|p=18461615|t=2008. Prevalence of erythrovirus genotypes in the myocardium of patients with dilated cardiomyopathy |pdf=|usr=}}{{18461615}} gab.com Text Prevalence of erythrovirus genotypes in the myocardium of patients with dilated cardiomyopathy JO: J Med Virol http://www.kidney.de/pget.php?&tw=1&pmid=18461615 #FOAvip Parvovirus B19 (PVB19) is a member of the human erythrovirus family detected frequently in endomyocardial biopsies from patients with dilated cardiomyopathy. Human erythroviruses cluster into three genotypes 1-3 which share a high degree of homology between major structural proteins and may cause indistinguishable infections clinically and serologically. In human cardiac tissue erythrovirus genotypes other than PVB19 have not yet been reported. Three hundred seventeen consecutive patients with symptomatic dilated cardiomyopathy (median left ventricular ejection fraction: 28.6%, range 5-45%) who underwent endomyocardial biopsy for the elucidation of the etiology, were analyzed using a new consensus PCR assay designed for the detection of the three erythrovirus genotype sequences. Endomyocardial biopsies of 151 (47.6%) patients were erythrovirus-positive. Genotype 1 specific sequences were detected in 43/151 (28.5%) of positive biopsy samples, whereas genotype 2-specific sequences so far considered rare in human disease and not yet been described in human heart tissue was identified in 108/151 (71.5%) of virus-positive endomyocardial biopsies with a preference in patients above 50 years of age. In spite of younger age, systolic left ventricular dysfunction of genotype 1-positive patients was significantly reduced as compared to genotype 2-positive patients (24.4+/-10.4% vs. 31.0+/-9.5%, P=0.0001) at the initial presentation. The data show that two genetically distinct erythrovirus variants with a different age distribution are detectable in endomyocardial biopsies of patients with dilated cardiomyopathy. The erythrovirus genotype 2, not described previously in human heart tissue, is highly prevalent in the heart but the less prevalent genotype 1 is associated with more severe disturbed cardiac function. Twit Text FOAVip Prevalence of erythrovirus genotypes in the myocardium of patients with dilated cardiomyopathy ????J Med Virol http://www.kidney.de/pget.php?&tw=1&pmid=18461615 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=18461615 #FOAvip English Wikipedia <ref>{{Cite pmid|18461615}}</ref> Prevalence of erythrovirus genotypes in the myocardium of patients with dilated cardiomyopathy #MMPMID18461615 Kuhl U; Lassner D; Pauschinger M; Gross UM; Seeberg B; Noutsias M; Poller W; Schultheiss HP J Med Virol 2008[Jul]; 80 (7): 1243-51 PMID18461615show ga Parvovirus B19 (PVB19) is a member of the human erythrovirus family detected frequently in endomyocardial biopsies from patients with dilated cardiomyopathy. Human erythroviruses cluster into three genotypes 1-3 which share a high degree of homology between major structural proteins and may cause indistinguishable infections clinically and serologically. In human cardiac tissue erythrovirus genotypes other than PVB19 have not yet been reported. Three hundred seventeen consecutive patients with symptomatic dilated cardiomyopathy (median left ventricular ejection fraction: 28.6%, range 5-45%) who underwent endomyocardial biopsy for the elucidation of the etiology, were analyzed using a new consensus PCR assay designed for the detection of the three erythrovirus genotype sequences. Endomyocardial biopsies of 151 (47.6%) patients were erythrovirus-positive. Genotype 1 specific sequences were detected in 43/151 (28.5%) of positive biopsy samples, whereas genotype 2-specific sequences so far considered rare in human disease and not yet been described in human heart tissue was identified in 108/151 (71.5%) of virus-positive endomyocardial biopsies with a preference in patients above 50 years of age. In spite of younger age, systolic left ventricular dysfunction of genotype 1-positive patients was significantly reduced as compared to genotype 2-positive patients (24.4+/-10.4% vs. 31.0+/-9.5%, P=0.0001) at the initial presentation. The data show that two genetically distinct erythrovirus variants with a different age distribution are detectable in endomyocardial biopsies of patients with dilated cardiomyopathy. The erythrovirus genotype 2, not described previously in human heart tissue, is highly prevalent in the heart but the less prevalent genotype 1 is associated with more severe disturbed cardiac function. |Adult[MESH] |Aged[MESH] |Amino Acid Sequence[MESH] |Base Sequence[MESH] |Capsid Proteins/chemistry[MESH] |Cardiomyopathy, Dilated/*virology[MESH] |Erythrovirus/genetics/*isolation & purification[MESH] |Female[MESH] |Genotype[MESH] |Heart/*virology[MESH] |Humans[MESH] |Male[MESH] |Middle Aged[MESH] |Molecular Sequence Data[MESH] |Parvoviridae Infections/*virology[MESH] |Prevalence[MESH] |Sequence Alignment[MESH]Prevalence of erythrovirus genotypes in the myocardium of patients wit(epmc).pdf DeepDyve Pubget Overpricing