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10.1002/dvdy.21540 http://scihub22266oqcxt.onion/10.1002/dvdy.21540 18435467!3304540!18435467     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Dev+Dyn 2008 ; 237 (8): 1972-81 Nephropedia Template TP {{tp|p=18435467|t=2008. Building it up and taking it down: the regulation of vertebrate ciliogenesis |pdf=|usr=}}{{18435467}} gab.com Text Building it up and taking it down: the regulation of vertebrate ciliogenesis JO: Dev Dyn http://www.kidney.de/pget.php?&tw=1&pmid=18435467 #FOAvip Primary cilia project from the surface of most vertebrate cells, and function in sensation and signaling during both development and adult tissue homeostasis. Mounting evidence links ciliary defects with a wide variety of diseases, underscoring the importance of understanding how these dynamic organelles are assembled and maintained. However, despite their physiological and clinical relevance, the logic and machinery that regulate ciliogenesis remain largely enigmatic. Here, we summarize emerging data that connect the assembly and disassembly of the primary cilium to cell cycle progression and we examine how determinants of cell architecture, including the planar cell polarity pathway, may regulate ciliogenesis. Additionally, identification of the genes underlying diverse ciliopathies in human patients is shedding light on the regulation of the formation of this complex organelle. Twit Text FOAVip Building it up and taking it down: the regulation of vertebrate ciliogenesis ????Dev Dyn http://www.kidney.de/pget.php?&tw=1&pmid=18435467 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=18435467 #FOAvip English Wikipedia <ref>{{Cite pmid|18435467}}</ref> Building it up and taking it down: the regulation of vertebrate ciliogenesis #MMPMID18435467 Santos N; Reiter JF Dev Dyn 2008[Aug]; 237 (8): 1972-81 PMID18435467show ga Primary cilia project from the surface of most vertebrate cells, and function in sensation and signaling during both development and adult tissue homeostasis. Mounting evidence links ciliary defects with a wide variety of diseases, underscoring the importance of understanding how these dynamic organelles are assembled and maintained. However, despite their physiological and clinical relevance, the logic and machinery that regulate ciliogenesis remain largely enigmatic. Here, we summarize emerging data that connect the assembly and disassembly of the primary cilium to cell cycle progression and we examine how determinants of cell architecture, including the planar cell polarity pathway, may regulate ciliogenesis. Additionally, identification of the genes underlying diverse ciliopathies in human patients is shedding light on the regulation of the formation of this complex organelle. |Animals[MESH] |Cell Cycle/*physiology[MESH] |Cilia/*physiology[MESH] |Eukaryotic Cells/*cytology/physiology/*ultrastructure[MESH] |Humans[MESH] |Signal Transduction/physiology[MESH]Building it up and taking it down: the regulation of vertebrate ciliog(epmc).pdf DeepDyve Pubget Overpricing