Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText.
Kick-your-searchterm to multiple Engines kick-your-query now !>
A dictionary by aggregated review articles of nephrology, medicine and the life sciences
Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

suck abstract from ncbi


suck pdf from google scholar
PDF vom PMID18393310 :   free

suck abstract from ncbi

Nephropedia Template TP Text

Twit Text FOAVip

Twit Text #

English Wikipedia

  • Assembly of primary cilia #MMPMID18393310
  • Pedersen LB; Veland IR; Schroder JM; Christensen ST
  • Dev Dyn 2008[Aug]; 237 (8): 1993-2006 PMID18393310show ga
  • Primary cilia are microtubule-based, hair-like sensory organelles present on the surface of most growth-arrested cells in our body. Recent research has demonstrated a crucial role for primary cilia in regulating vertebrate developmental pathways and tissue homeostasis, and defects in genes involved in primary cilia assembly or function have been associated with a panoply of disorders and diseases, including polycystic kidney disease, left-right asymmetry defects, hydrocephalus, and Bardet Biedl Syndrome. Here we provide an up-to-date review focused on the molecular mechanisms involved in the assembly of primary cilia in vertebrate cells. We present an overview of the early stages of the cilia assembly process, as well as a description of the intraflagellar transport (IFT) system. IFT is a highly conserved process required for assembly of almost all eukaryotic cilia and flagella, and much of our current knowledge about IFT is based on studies performed in Chlamydomonas and Caenorhabditis elegans. Therefore, our review of the IFT literature includes studies performed in these two model organisms. The role of several non-IFT proteins (e.g., centrosomal proteins) in the ciliary assembly process is also discussed.
  • |Animals[MESH]
  • |Caenorhabditis elegans/*cytology[MESH]
  • |Chlamydomonas/*cytology[MESH]
  • |Cilia/*physiology[MESH]
  • |Eukaryotic Cells/*physiology/*ultrastructure[MESH]
  • |Models, Animal[MESH]

  • DeepDyve
  • Pubget Overpricing
  • suck abstract from ncbi

    1993 8.237 2008