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10.1111/j.1751-553X.2008.01052.x http://scihub22266oqcxt.onion/10.1111/j.1751-553X.2008.01052.x 18384396!ä!18384396 Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=18384396&cmd=llinks): Failed to open stream: HTTP request failed! 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Promoter methylation of P15(INK4B) gene is possibly associated with parvovirus B19 infection in adult acute leukemias |pdf=|usr=}}{{18384396}} gab.com Text Promoter methylation of P15(INK4B) gene is possibly associated with parvovirus B19 infection in adult acute leukemias JO: Int J Lab Hematol http://www.kidney.de/pget.php?&tw=1&pmid=18384396 #FOAvip In this study, we examined the P15(INK4B) gene promoter methylation in patients with myelodysplastic syndrome and acute leukemia and its possible relationship with parvovirus B19 and Epstein-Barr virus infections. P15(INK4B) methylation frequency was significantly higher in acute leukemia patients than in that of non-malignant patients (P < 0.05). When the patients with myelodysplastic syndrome were included, no significant difference was found between these groups regarding the methylation status. The possible correlation between P15(INK4B) promoter methylation and parvovirus B19 infection was observed in adult acute leukemia patients (P < 0.05). However, no similar relationship in EBV-infected patients was observed. To the best of our knowledge, this is the first report showing the possible association between P15(INK4B) promoter methylation and parvovirus B19 infection in acute leukemia. Twit Text FOAVip Promoter methylation of P15(INK4B) gene is possibly associated with parvovirus B19 infection in adult acute leukemias ????Int J Lab Hematol http://www.kidney.de/pget.php?&tw=1&pmid=18384396 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=18384396 #FOAvip English Wikipedia <ref>{{Cite pmid|18384396}}</ref> Promoter methylation of P15(INK4B) gene is possibly associated with parvovirus B19 infection in adult acute leukemias #MMPMID18384396 Yalcin A; Serin MS; Emekdas G; Tiftik N; Aslan G; Eskandari G; Tezcan S Int J Lab Hematol 2009[Aug]; 31 (4): 407-19 PMID18384396show ga In this study, we examined the P15(INK4B) gene promoter methylation in patients with myelodysplastic syndrome and acute leukemia and its possible relationship with parvovirus B19 and Epstein-Barr virus infections. P15(INK4B) methylation frequency was significantly higher in acute leukemia patients than in that of non-malignant patients (P < 0.05). When the patients with myelodysplastic syndrome were included, no significant difference was found between these groups regarding the methylation status. The possible correlation between P15(INK4B) promoter methylation and parvovirus B19 infection was observed in adult acute leukemia patients (P < 0.05). However, no similar relationship in EBV-infected patients was observed. To the best of our knowledge, this is the first report showing the possible association between P15(INK4B) promoter methylation and parvovirus B19 infection in acute leukemia. |*DNA Methylation[MESH] |*Parvovirus B19, Human[MESH] |Acute Disease[MESH] |Adolescent[MESH] |Adult[MESH] |Aged[MESH] |Cyclin-Dependent Kinase Inhibitor p15/*genetics[MESH] |Epstein-Barr Virus Infections/complications/genetics[MESH] |Female[MESH] |Genetic Predisposition to Disease[MESH] |Herpesvirus 4, Human[MESH] |Humans[MESH] |Leukemia/*virology[MESH] |Male[MESH] |Middle Aged[MESH] |Myelodysplastic Syndromes/virology[MESH] |Parvoviridae Infections/complications/*genetics[MESH] |Promoter Regions, Genetic[MESH]Promoter methylation of P15(INK4B) gene is possibly associated with pa(epmc).pdf DeepDyve Pubget Overpricing