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10.1177/147323000803600215 http://scihub22266oqcxt.onion/10.1177/147323000803600215 18380943!ä!18380943 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Int+Med+Res 2008 ; 36 (2): 322-8 Nephropedia Template TP {{tp|p=18380943|t=2008. Gabexate mesilate suppresses influenza pneumonia in mice through inhibition of cytokines |pdf=|usr=}}{{18380943}} gab.com Text Gabexate mesilate suppresses influenza pneumonia in mice through inhibition of cytokines JO: J Int Med Res http://www.kidney.de/pget.php?&tw=1&pmid=18380943 #FOAvip Gabexate mesilate is a synthetic protease inhibitor that is effective for acute pancreatitis. The effect of gabexate mesilate in influenza pneumonia in mice was investigated by examining the changes in pulmonary inflammatory cytokines and chemokines. Pathological changes in the lungs of treated mice were extremely mild, compared with changes in infected, untreated mice. Intrapulmonary levels of interleukin-6 and macrophage inflammatory protein-2 decreased in treated mice compared with untreated mice, despite similar viral titres in the lungs. Survival terms for treated and untreated groups were similar. These data indicate that gabexate mesilate has beneficial effects on influenza pneumonia, which may be due to the modulation of inflammatory cytokine/chemokine responses. Twit Text FOAVip Gabexate mesilate suppresses influenza pneumonia in mice through inhibition of cytokines ????J Int Med Res http://www.kidney.de/pget.php?&tw=1&pmid=18380943 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=18380943 #FOAvip English Wikipedia <ref>{{Cite pmid|18380943}}</ref> Gabexate mesilate suppresses influenza pneumonia in mice through inhibition of cytokines #MMPMID18380943 Kosai K; Seki M; Yanagihara K; Nakamura S; Kurihara S; Izumikawa K; Kakeya H; Yamamoto Y; Tashiro T; Kohno S J Int Med Res 2008[Mar]; 36 (2): 322-8 PMID18380943show ga Gabexate mesilate is a synthetic protease inhibitor that is effective for acute pancreatitis. The effect of gabexate mesilate in influenza pneumonia in mice was investigated by examining the changes in pulmonary inflammatory cytokines and chemokines. Pathological changes in the lungs of treated mice were extremely mild, compared with changes in infected, untreated mice. Intrapulmonary levels of interleukin-6 and macrophage inflammatory protein-2 decreased in treated mice compared with untreated mice, despite similar viral titres in the lungs. Survival terms for treated and untreated groups were similar. These data indicate that gabexate mesilate has beneficial effects on influenza pneumonia, which may be due to the modulation of inflammatory cytokine/chemokine responses. |Animals[MESH] |Antiviral Agents/*administration & dosage[MESH] |Cell Line[MESH] |Cytokines/*antagonists & inhibitors[MESH] |Disease Models, Animal[MESH] |Dogs[MESH] |Gabexate/*administration & dosage[MESH] |Influenza A Virus, H1N1 Subtype/*drug effects/immunology[MESH] |Male[MESH] |Mice[MESH] |Mice, Inbred CBA[MESH] |Orthomyxoviridae Infections/*drug therapy/immunology/pathology[MESH] |Pneumonia, Viral/*drug therapy/immunology/pathology[MESH]Gabexate mesilate suppresses influenza pneumonia in mice through inhib(epmc).pdf DeepDyve Pubget Overpricing