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10.1002/dvdy.21493 http://scihub22266oqcxt.onion/10.1002/dvdy.21493 18366139!ä!18366139 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Dev+Dyn 2008 ; 237 (8): 1955-9 Nephropedia Template TP {{tp|p=18366139|t=2008. The primary cilium as a gravitational force transducer and a regulator of transcriptional noise |pdf=|usr=}}{{18366139}} gab.com Text The primary cilium as a gravitational force transducer and a regulator of transcriptional noise JO: Dev Dyn http://www.kidney.de/pget.php?&tw=1&pmid=18366139 #FOAvip Circumstantial evidence has suggested that the primary cilium might function as a gravity sensor. Direct evidence of its gravity-sensing function has recently been provided by studies of rohon beard neurons. These neurons showed changes in the variability of gene expression levels that are linked to the cyclic changes in the Earth's gravitational field due to the Sun and Moon. These cyclic changes also cause the tides. Rohon beard neurons, after the primary cilia have been selectively destroyed, no longer show changes in gene expression variability linked to the cyclic changes in Earth's gravitational field. After the neurons regrow their primary cilia, the link between variability in gene expression levels and the Earth's changing gravitational field returns. This suggests two new functions for the primary cilia, detecting the cyclical changes in the Earth's gravitational field and transducing those changes into changes in the variability (stochastic nature) of gene expression. Twit Text FOAVip The primary cilium as a gravitational force transducer and a regulator of transcriptional noise ????Dev Dyn http://www.kidney.de/pget.php?&tw=1&pmid=18366139 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=18366139 #FOAvip English Wikipedia <ref>{{Cite pmid|18366139}}</ref> The primary cilium as a gravitational force transducer and a regulator of transcriptional noise #MMPMID18366139 Moorman SJ; Shorr AZ Dev Dyn 2008[Aug]; 237 (8): 1955-9 PMID18366139show ga Circumstantial evidence has suggested that the primary cilium might function as a gravity sensor. Direct evidence of its gravity-sensing function has recently been provided by studies of rohon beard neurons. These neurons showed changes in the variability of gene expression levels that are linked to the cyclic changes in the Earth's gravitational field due to the Sun and Moon. These cyclic changes also cause the tides. Rohon beard neurons, after the primary cilia have been selectively destroyed, no longer show changes in gene expression variability linked to the cyclic changes in Earth's gravitational field. After the neurons regrow their primary cilia, the link between variability in gene expression levels and the Earth's changing gravitational field returns. This suggests two new functions for the primary cilia, detecting the cyclical changes in the Earth's gravitational field and transducing those changes into changes in the variability (stochastic nature) of gene expression. |Animals[MESH] |Cilia/*physiology[MESH] |Gene Expression Regulation/physiology[MESH] |Gravity Sensing/*physiology[MESH] |Neurons/*physiology/*ultrastructure[MESH] |Transcription, Genetic/*physiology[MESH]The primary cilium as a gravitational force transducer and a regulator(epmc).pdf DeepDyve Pubget Overpricing