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10.1002/jcp.21423 http://scihub22266oqcxt.onion/10.1002/jcp.21423 18330886!7166642!18330886     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Cell+Physiol 2008 ; 216 (2): 366-77 Nephropedia Template TP {{tp|p=18330886|t=2008. Viral vectors for production of recombinant proteins in plants |pdf=|usr=}}{{18330886}} gab.com Text Viral vectors for production of recombinant proteins in plants JO: J Cell Physiol http://www.kidney.de/pget.php?&tw=1&pmid=18330886 #FOAvip Global demand for recombinant proteins has steadily accelerated for the last 20 years. These recombinant proteins have a wide range of important applications, including vaccines and therapeutics for human and animal health, industrial enzymes, new materials and components of novel nano-particles for various applications. The majority of recombinant proteins are produced by traditional biological "factories," that is, predominantly mammalian and microbial cell cultures along with yeast and insect cells. However, these traditional technologies cannot satisfy the increasing market demand due to prohibitive capital investment requirements. During the last two decades, plants have been under intensive investigation to provide an alternative system for cost-effective, highly scalable, and safe production of recombinant proteins. Although the genetic engineering of plant viral vectors for heterologous gene expression can be dated back to the early 1980s, recent understanding of plant virology and technical progress in molecular biology have allowed for significant improvements and fine tuning of these vectors. These breakthroughs enable the flourishing of a variety of new viral-based expression systems and their wide application by academic and industry groups. In this review, we describe the principal plant viral-based production strategies and the latest plant viral expression systems, with a particular focus on the variety of proteins produced and their applications. We will summarize the recent progress in the downstream processing of plant materials for efficient extraction and purification of recombinant proteins. Twit Text FOAVip Viral vectors for production of recombinant proteins in plants ????J Cell Physiol http://www.kidney.de/pget.php?&tw=1&pmid=18330886 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=18330886 #FOAvip English Wikipedia <ref>{{Cite pmid|18330886}}</ref> Viral vectors for production of recombinant proteins in plants #MMPMID18330886 Lico C; Chen Q; Santi L J Cell Physiol 2008[Aug]; 216 (2): 366-77 PMID18330886show ga Global demand for recombinant proteins has steadily accelerated for the last 20 years. These recombinant proteins have a wide range of important applications, including vaccines and therapeutics for human and animal health, industrial enzymes, new materials and components of novel nano-particles for various applications. The majority of recombinant proteins are produced by traditional biological "factories," that is, predominantly mammalian and microbial cell cultures along with yeast and insect cells. However, these traditional technologies cannot satisfy the increasing market demand due to prohibitive capital investment requirements. During the last two decades, plants have been under intensive investigation to provide an alternative system for cost-effective, highly scalable, and safe production of recombinant proteins. Although the genetic engineering of plant viral vectors for heterologous gene expression can be dated back to the early 1980s, recent understanding of plant virology and technical progress in molecular biology have allowed for significant improvements and fine tuning of these vectors. These breakthroughs enable the flourishing of a variety of new viral-based expression systems and their wide application by academic and industry groups. In this review, we describe the principal plant viral-based production strategies and the latest plant viral expression systems, with a particular focus on the variety of proteins produced and their applications. We will summarize the recent progress in the downstream processing of plant materials for efficient extraction and purification of recombinant proteins. |*Genetic Vectors/genetics/metabolism[MESH] |*Plant Proteins/genetics/metabolism[MESH] |*Plant Viruses/genetics/metabolism[MESH] |*Plants/genetics/metabolism/virology[MESH] |*Recombinant Proteins/genetics/metabolism[MESH] |Animals[MESH] |Antibodies, Monoclonal/genetics/metabolism[MESH] |Antigens/genetics/metabolism[MESH] |Biomedical Engineering[MESH] |Humans[MESH] |Nanotechnology[MESH] |Plants, Genetically Modified[MESH]Viral vectors for production of recombinant proteins in plants (epmc).pdf DeepDyve Pubget Overpricing