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10.1007/BF00498591 http://scihub22266oqcxt.onion/10.1007/BF00498591 181683!ä!181683 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Naunyn+Schmiedebergs+Arch+Pharmacol 1976 ; 292 (2): 189-92 Nephropedia Template TP {{tp|p=181683|t=1976. Non-specific inhibition of membrane-ATPase by amiloride: a comparative in vivo and in vitro study with ouabain |pdf=|usr=}}{{181683}} gab.com Text Non-specific inhibition of membrane-ATPase by amiloride: a comparative in vivo and in vitro study with ouabain JO: Naunyn Schmiedebergs Arch Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=181683 #FOAvip The submaxillary duct epithelium, which actively transports Na+ (rabbit) and, in addition, K+ and H+/HCO-/3 (rat), was used as a model epithelium to compare the effects of ouabain and amiloride on transport parameters. 1. Ouabain was only effective from the interstitial side, amiloride, however, only from the luminal side. Amiloride induced effects on transport of the ions were seen within less than 1 s, ouabain effects, however, only after minutes. 2. Ouabain inhibited in a parallel fashion the Na+ transport potential and the Na+-K+-ATPase activity. It had no effect on the Mg2+-ATPase and the HCO-/3-ATPase. 3. Amiloride also inhibited the Na+ transport potential and the Na+-K+-ATPase; however, the Na+ transport potential was significantly more sensitive to amiloride than the Na+-K+-ATPase. 4. Amiloride inhibited in a similar fashion the Na+-K+-ATPase, the Mg2+-ATPase and the HCO-/3-ATPase, but did not influence active HCO-/3 secretion. 5. It is concluded that the amiloride induced effects on the membrane ATPases are non-specific. Twit Text FOAVip Non-specific inhibition of membrane-ATPase by amiloride: a comparative in vivo and in vitro study with ouabain ????Naunyn Schmiedebergs Arch Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=181683 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=181683 #FOAvip English Wikipedia <ref>{{Cite pmid|181683}}</ref> Non-specific inhibition of membrane-ATPase by amiloride: a comparative in vivo and in vitro study with ouabain #MMPMID181683 Knauf H; Simon B; Wais U Naunyn Schmiedebergs Arch Pharmacol 1976[]; 292 (2): 189-92 PMID181683show ga The submaxillary duct epithelium, which actively transports Na+ (rabbit) and, in addition, K+ and H+/HCO-/3 (rat), was used as a model epithelium to compare the effects of ouabain and amiloride on transport parameters. 1. Ouabain was only effective from the interstitial side, amiloride, however, only from the luminal side. Amiloride induced effects on transport of the ions were seen within less than 1 s, ouabain effects, however, only after minutes. 2. Ouabain inhibited in a parallel fashion the Na+ transport potential and the Na+-K+-ATPase activity. It had no effect on the Mg2+-ATPase and the HCO-/3-ATPase. 3. Amiloride also inhibited the Na+ transport potential and the Na+-K+-ATPase; however, the Na+ transport potential was significantly more sensitive to amiloride than the Na+-K+-ATPase. 4. Amiloride inhibited in a similar fashion the Na+-K+-ATPase, the Mg2+-ATPase and the HCO-/3-ATPase, but did not influence active HCO-/3 secretion. 5. It is concluded that the amiloride induced effects on the membrane ATPases are non-specific. |4-Nitrophenylphosphatase/antagonists & inhibitors[MESH] |Adenosine Triphosphatases/*antagonists & inhibitors[MESH] |Amiloride/*pharmacology[MESH] |Animals[MESH] |Bicarbonates/metabolism[MESH] |Biological Transport, Active/drug effects[MESH] |In Vitro Techniques[MESH] |Magnesium/metabolism[MESH] |Membrane Potentials/drug effects[MESH] |Ouabain/*pharmacology[MESH] |Potassium/metabolism[MESH] |Pyrazines/*pharmacology[MESH] |Rabbits[MESH] |Rats[MESH] |Sodium/metabolism[MESH]Non-specific inhibition of membrane-ATPase by amiloride: a comparative(epmc).pdf DeepDyve Pubget Overpricing